نتایج جستجو برای: stereocilia

تعداد نتایج: 641  

Journal: :Journal of neurophysiology 2008
A Li J Xue E H Peterson

Hair bundles are critical to mechanotransduction by vestibular hair cells, but quantitative data are lacking on vestibular bundles in mice or other mammals. Here we quantify bundle heights and their variation with macular locus and hair cell type in adult mouse utricular macula. We also determined that macular organization differs from previous reports. The utricle has approximately 3,600 hair ...

Journal: :Experimental animals 2012
Yoshiaki Kikkawa Yuta Seki Kazuhiro Okumura Yasuhiro Ohshiba Yuki Miyasaka Sari Suzuki Mao Ozaki Kunie Matsuoka Yoshihiro Noguchi Hiromichi Yonekawa

Hearing is a major factor in human quality of life. Mouse models are important tools for discovering the genes that are responsible for genetic hearing loss, and these models often allow the processes that regulate the onset of deafness in humans to be analyzed. Thus far, in the study of hearing and deafness, at least 400 mutants with hearing impairments have been identified in laboratory mouse...

Journal: :The Journal of Cell Biology 1980
L G Tilney D J Derosier M J Mulroy

Within each tapering stereocilium of the cochlea of the alligator lizard is a bundle of actin filaments with > 3,000 filaments near the tip and only 18-29 filaments at the base where the bundle enters into the cuticular plate; there the filaments splay out as if on the surface of a cone, forming the rootlet. Decoration of the hair cells with subfragment 1 of myosin reveals that all the filament...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2006
Zubair M Ahmed Richard Goodyear Saima Riazuddin Ayala Lagziel P Kevin Legan Martine Behra Shawn M Burgess Kathryn S Lilley Edward R Wilcox Sheikh Riazuddin Andrew J Griffith Gregory I Frolenkov Inna A Belyantseva Guy P Richardson Thomas B Friedman

Sound and acceleration are detected by hair bundles, mechanosensory structures located at the apical pole of hair cells in the inner ear. The different elements of the hair bundle, the stereocilia and a kinocilium, are interconnected by a variety of link types. One of these links, the tip link, connects the top of a shorter stereocilium with the lateral membrane of an adjacent taller stereocili...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2009
Jung-Bum Shin Peter G Gillespie

T he inner ear’s sensory cells, the hair cells, mediate mechanotransduction, which enables us to experience sound and movements of the head. Protruding from the apical portion of a hair cell, a hair bundle is formed from actin-rich stereocilia, which are arrayed with increasing length in a staircase formation; mechanical stimuli that deflect the bundle toward the tallest stereocilia open cation...

2003
LEWIS G. TILNEY DAVID J. DEROSIER MICHAEL J. MULROY

Within each tapering stereocilium of the cochlea of the alligator lizard is a bundle of actin filaments with >3,000 filaments near the tip and only 18-29 filaments at the base where the bundle enters into the cuticular plate; there the filaments splay out as if on the surface of a cone, forming the rootlet. Decoration of the hair cells with subfragment 1 of myosin reveals that all the filaments...

Journal: :Proceedings of the National Academy of Sciences 1990

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