Stevia rebaudiana Bertoni is famous for sweetness due to the content of steviol glycosides (SG). This study aimed determine effect SG (stevioside, rebaudioside A) and on adipogenesis lipogenesis in 3T3-L1 model. Test compounds were also analysed their ability affect glucose uptake hypertrophied insulin-resistant adipocytes. The most active compound modulating adipogenesis, insulin resistance wa...

Basic hydrolysis of a dichloromethane extract of Stevia lucida yielded (4R,5S,7R,9R,10R,11R)-7,9-dihydroxylongipin-2-en-1-one (1), which was oxidized and subjected to acidic conditions to generate the new seco-moreliane derivative 3. The structure of 3 was established based on NMR data interpretation and confirmed computationally. A plausible mechanism for the carbocationic rearrangement of the...

Purpose: The purpose of the study is to evaluate the antimicrobial and antitumor activities of Stevia rebaudiana (Asteraceae) leaf extracts. Methods: Four solvent extracts (ethyl acetate, acetone, chloroform and water) of Stevia rebaudiana leaves were investigated against Staphylococcus aureus, Salmonella typhi, Escherichia coli, Bacillus subtilis, Aeromonas hydrophila and Vibrio cholerae by us...

Heritability estimates of traits assist breeders in optimizing cultivar development and can help predict gain from selection breeding programs. Narrow-sense heritabilities were measured agronomic glycoside concentration four elite stevia (Stevia rebaudiana Bertoni) populations using half-sib family analysis. Gain at 20% intensity was estimated for morphological, yield, traits. Experiments condu...