In recent years, dramatic improvements in kidney transplantation, together with a rising incidence of diseases such as diabetes, have led to an increasing demand for deceased donor kidneys for transplantation. Hence, it has been necessary to expand the kidney donor pool by using organs once considered unsuitable for transplantation. These higher risk kidneys are typically from older donors with...

Alterations in the metabolism of Lupinus albus organs that result from and subsequently follow a period of severe water deficit (WD) are described. By means of 13C-nuclear magnetic resonance (NMR), changes in the major metabolites were monitored in several plant organs (leaflets and petiole, roots, stem stele and cortex). During the stress, most of the leaves were lost and the stem functioned a...

Turions are frost resistant, vegetative dormant organs produced by aquatic plants. Tissue N, P, K, Ca, and Mg content was estimated in turions of 5 rooting, non-carnivorous plant species of the genera Caldesia, Hydrocharis, and Potamogeton and in 7 rootless carnivorous plant species of the genera Aldrovanda and Utricularia, and compared with concentrations of these nutrients in ambient waters e...

The lysosomal storage disorder galactosialidosis results from a primary deficiency of the protective protein/cathepsin A (PPCA), which in turn affects the activities of beta-galactosidase and neuraminidase. Mice homozygous for a null mutation at the PPCA locus present with signs of the disease shortly after birth and develop a phenotype closely resembling human patients with galactosialidosis. ...

Here, we tested whether rapid changes in carbohydrate transport and partitioning to storage organs would be induced by jasmonic acid (JA), a plant-produced signal of herbivore attack known to induce resistance. Carbon-11, introduced as (11)CO(2), was used to track real-time carbohydrate transport and partitioning nondestructively in Populus species before and 12 h after application of JA to a s...

We investigated gene expression patterns that occur during taro corm development. Two-dimensional gel electrophoresis identified several different prevalent proteins that accumulate during corm development. Microsequencing studies indicated that some of these proteins are related to taste-modifying proteins, such as curculin and miraculin, and proteins found in other storage organs, such as spo...

Physiological changes in females during and after mating are triggered by seminal fluid components in conjunction with female-derived molecules. In insects, these changes include increased egg production, storage of sperm, and changes in muscle contraction within the reproductive tract (RT). Such postmating changes have been studied in dissected RT tissues, but understanding their coordination ...

1. The liver sinusoid is lined with sinusoidal cells (endothelial cells), Kupffer cells, and fat storage cells (also called stellate or Ito cells), which perform important metabolic functions and defend the liver. 2. The liver plays an important role in maintaining blood glucose levels and in metabolizing drugs and toxic substances. 3. The liver has a remarkable capacity to regenerate. 4. The l...