Cheekula, Siva Kumar. M.S. Department of Computer Science and Engineering, Wright State University, 2017. Characterizing Concepts in Taxonomy for Entity Recommendations. Entity recommendation systems are enormously popular on the Web. These systems harness manually crafted taxonomies for improving recommendations. For example, Yahoo created the Open Directory Project for search and recommendati...

To cite: Kumar MH, Kumar MS, Siva Kumar V, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2015211429 DESCRIPTION 3-M syndrome is a rare autosomal recessive disorder characterised by short stature, dysmorphic facial features and skeletal abnormalities. Individuals with 3-M syndrome have a recognisable pattern of features including a triangular face with poi...

BACKGROUND Small-vessel dysfunction may be an important consequence of chronic hyperglycemia. We examined the association between gestational diabetes mellitus (GDM), a state of transient hyperglycemia during pregnancy, and retinal microvascular changes in pregnant women at 26-28 weeks of pregnancy. METHODS A total of 1136 pregnant women with singleton pregnancies were recruited during their ...

ACKNOWLEDGEMENTS First and foremost, I express my sincere gratitude to Dr. C. Chandra Sekhar for his guidance throughout my research work. His invaluable advise and constructive criticism, patience and constant encouragement have motivated me throughout my research work. Although he was very busy with the administration work, he was always available to steer my project in methodical way. His cl...

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CC3 is a metastasis suppressor that inhibits metastasis of the variant small cell lung carcinoma (v-SCLC) by predisposing cells to apoptosis. The same protein was also reported as a cellular cofactor, TIP30, which stimulates HIV-1 Tat-activated transcription by interacting with both Tat and RNA polymerase II. We report here that TIP30/CC3 is a novel serine/threonine kinase. It phosphorylates th...

Animal societies are aggregations of cooperating individuals that are isolated from other societies by limitations of dispersal and/or hostile exclusion mechanisms. The individuals within them are more related to the members of their own society than to random individuals in the population at large and quite often this relatedness is high because societies are families or groups of families. Fo...

A pathogenic role of p53 in AKI was suggested a decade ago but remains controversial. Indeed, recent work indicates that inhibition of p53 protects against ischemic AKI in rats but exacerbates AKI in mice. One intriguing possibility is that p53 has cell type-specific roles in AKI. To determine the role of tubular p53, we generated two conditional gene knockout mouse models, in which p53 is spec...

Many emergency patients present with cardiac arrhythmias requiring emergency direct current countershock cardioversion (DCCV) as a part of their management. Almost all require sedation to facilitate the procedure. Propofol has been used for procedural sedation in Emergency Medicine since 1995. In 1996, in a review article in Anaesthesia, it was recommended as the drug which most closely approac...

Cardiomyocytes in postnatal heart are terminally differentiated and thus possess limited capacity to regenerate. Loss of cardiomyocytes through apoptosis and necrosis can lead to heart failure and other serious consequences. Compared to mammals, substantially less research has been conducted on chicken cardiomyocytes; thus, the apoptosis pathways and many relevant genes remain unknown. To eluci...