نتایج جستجو برای: streptokinase thrombolytic activity

تعداد نتایج: 1141962  

باغبانی آرانی, فهیمه, رضایی, مهسا, عربی میانرودی, رضا,

Streptokinase is one of the best known thrombolytic agents with widespread clinical use. However, its use is not risk-free due to its immunogenicity, hemorrhagic complications and relatively short half-life in circulation. Specific PEGylation of cysteine residue is a useful technique for reducing most of these complications. The aim of this study was designing and producing a cysteine containin...

Journal: :Journal of the American College of Cardiology 2000
M Ozkan C Kaymaz C Kirma K Sönmez N Ozdemir M Balkanay C Yakut U Deligönül

OBJECTIVE We analyzed the results of intravenous thrombolytic treatment under transesophageal echocardiographic (TEE) guidance in prosthetic valve thrombosis. BACKGROUND Thrombotic occlusion of prosthetic valves continues to be an uncommon but serious complication. Intravenous thrombolytic treatment has been proposed as an alternative to surgical intervention. METHODS In a four-year period,...

Journal: :Nusantara bioscience 2022

Moringa oleifera Lam. (Family Moringaceae) is a medium sized perennial tree, commonly known as drumstick horse raddish miracle sahjan, shobhanjana, munga arak, etc., in different languages. Leaves, flowers and pods of the plant are edible. Various parts utilized for treatment several diseases by ethnic communities, including heart ailments. Leaves M. were assessed preliminary qualitative phytoc...

Journal: :Saudi medical journal 2009
Hamoud Y Obied Mohammed F Ibrahim Bendehiba S Latroche Maya M Mroue

Thrombosis of a mechanical prosthetic valve is a serious and fortunately it is a rare complication of cardiac valve replacement. We present a case of prosthetic mechanical valve On-X 31/33 mm thrombosis thrombus size 8 x 14 mm on a mitral position, which was treated with a successful intravenous thrombolytic therapy of streptokinase infusion over 10 hours repeated twice with no complications.

Journal: :Neurosciences 2005
Tarig S Al-Khuwaitir Bashir A Wani Helmi A Dawood Mohammed A Khan

Thrombolytic therapy is the modality of choice for the treatment of life threatening thrombosis in various vascular territories and nowadays, is used extensively in the setting of acute myocardial infarction. There is, however, the omnipresent danger of serious bleeding inherently associated with the use of all thrombolytics which if it occurs in the brain, can lead to potentially serious neuro...

Journal: :Circulation 1991
J L Anderson S G Sorensen F L Moreno R A Hackworthy K F Browne H T Dale F Leya V Dangoisse H W Eckerson V J Marder

Thrombolytic therapy has been shown to improve clinical outcome when administered early after the onset of symptoms of acute myocardial infarction; the mechanism of benefit is believed to be reestablishment and maintenance of coronary artery patency. Anistreplase is a second generation thrombolytic agent that is easily administered and has a long duration of action. To compare anistreplase (30 ...

Journal: :Indian journal of medical sciences 2005
S K Diwedi J S Hiremath P G Kerkar Krishna N Reddy C N Manjunath S S Ramesh S Prabhavati M Dhobe Kavita Singh P Bhusari Raman Rao

BACKGROUND Streptokinase is the most widely used thrombolytic agent and can now be made using recombinant DNA technology. The present trial was initiated to assess an indigenous recombinant streptokinase (Shankinase, r-SK). AIM To compare the efficacy and safety of indigenous recombinant streptokinase (Shankinase, r-SK) and natural streptokinase (Streptase, n-SK). SETTINGS AND DESIGN Double...

Journal: :The American journal of cardiology 1988
W W O'Neill

Single-plane contrast ventriculography was performed on admission and before hospital discharge in more than 200 patients with acute myocardial infarction participating in a series of prospective clinical trials including intracoronary streptokinase, percutaneous transluminal coronary angioplasty (PTCA), intravenous tissue plasminogen activator (rt-PA) and thrombolysis (intravenous rt-PA or str...

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