نتایج جستجو برای: streptozotocin induced diabetes
تعداد نتایج: 1247110 فیلتر نتایج به سال:
Increasing the level of urea and uric acid is an associated complication of diabetes mellitus. Many spices and herbs are known to be hypoglycaemic. Olea europaea belonging to the family oleaceae is widely used in herbal medicine for the treatment of diabetes. The present study was carried out to investigate the role of the alcoholic extract from leaves of olive on level of urea and uric acid in...
Background and Objective: Chronic diabetes mellitus (DM) leads to cardiovascular dysfunction. Diosgenin is a natural steroidal saponin with cardiovascular protective potential. In this research study, the beneficial effect of diosgenin was evaluated on some markers of oxidative stress in cardia tissue of streptozotocin (STZ)-diabetic rats. Materials and Methods: Male Wistar rats (n = 28) were ...
Tephrosia purpurea has been reported to possess antidiabetic activity, however, its effects on cardiovascular complications and cataract associated with diabetes have not been studied. The objective of the present study was to investigate the effects of aqueous extract of Tephrosia purpurea on cardiovascular complications and cataract associated with streptozotocin-induced diabetes in rats. Spr...
objective(s): the object of the study is to examine the effects of δ9-tetrahydrocannabinol (thc) against oxidative stress in the blood and excretion of thc metabolites in urine of type 2 diabetic rats. materials and methods: the control (n=8), thc control (n=6), diabetes (n=8) and diabetes + thc (n=7) groups were created. type 2 diabetes was induced by nicotinamide (na, 85 mg/kg) + streptozotoc...
insulin dependent diabetes mellitus (iddm) results from irreversible loss of beta cells (β-cells) of the pancreas. a streptozotocin (stz)-induced diabetes in animal model mimics, in some aspects, recent onset iddm. this study was conducted to investigate the effect of nicotinamide on experimentally-induced iddm. thirty spraque dawley rats were divided into 3 groups; a control group, a diabetic ...
Introduction: Hyperalgesia is considered as one the marked signs of subchronic diabetes mellitus that could affect the life style of patients. Considering the evidence on the antidiabetic and analgesic effects of Nigella sativa (NS), this study was designed to investigate the analgesic effects of NS on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (STZ)-induc...
Objective(s) This investigation was conducted to evaluate the effects of diabetes on the structure and function of testicular tissue. Materials and Methods Diabetes was induced in male adult rats by a single intraperitoneal injection of streptozotocin. Body and testicular weight, hormonal analyses, histological and ultrastructural analyses were measured. Results The body and testicular we...
Increasing the level of urea and uric acid is an associated complication of diabetes mellitus. Many spices and herbs are known to be hypoglycaemic. Olea europaea belonging to the family oleaceae is widely used in herbal medicine for the treatment of diabetes. The present study was carried out to investigate the role of the alcoholic extract from leaves of olive on level of urea and uric acid in...
background and objective: teucrium polium (tp) has shown hypoglycemic effect in type 1 diabetes induced by single high dose of the cytotoxic agent streptozotocin (stz) in rats. this study was conducted to evaluate whether its aqueous extract could have such an effect in multiple low-dose stz-induced model of type 1 diabetes in rats. materials and methods: male wistar rats were divided into cont...
In the present study, powdered suspension of 'Glyoherb'- sugar control granules, a polyherbal formulation (manufactured by Dhanvantri Guj. herb., Valasan, Anand, Gujarat, India) was evaluated for its antihyperglycemic, antihyperlipidemic and antioxidant effects against normal and streptozotocin-induced diabetic rats. Type I diabetes was induced when streptozotocin 70 mg/kg was administered as a...
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