The extracellular matrix (ECM) is a complex assembly of structural proteins that provides physical support and biochemical signaling to cells in tissues. The mechanical properties of the ECM have been found to play a key role in regulating cell behaviors such as differentiation and malignancy. Gels formed from ECM protein biopolymers such as collagen or fibrin are commonly used for 3D cell cult...

The question is examined, whether the formally straightforward extension of Hooke’s time-honoured stress-strain relation to the four dimensions of special and of general relativity can make physical sense. The four-dimensional Hooke’s law is found able to account for the inertia of matter; in the flat space, slow motion approximation the field equations for the “displacement” four-vector field ...

A finite element model based on the layerwise theory is developed for the analysis of transverse cracking in cross-ply laminated beams. The numerical model is developed using the layerwise theory of Reddy, and the von Kármán type nonlinear strain field is adopted to accommodate the moderately large rotations of the beam. The finite element beam model is verified by comparing the present numeric...

In this paper, size-dependent effects on the vibration behavior of Timoshenko microbeams under pre-stress loading embedded in an elastic foundation, using modified strain gradient theory (MSGT) and surface stress effects, were studied. To consider the surface stress effects, the Gurtin–Murdoch continuum mechanical approach was employed. Using Hamilton’s principle, the governing equations of mot...

In this study, the vibration behavior of functional graded (FG) circular and annular nanoplate embedded in Visco-Pasternak foundation and coupled with temperature change is studied. It is assumed that a uniform radial magnetic field acts on the top surface of the plate and the magnetic permeability coefficient of the plate along its thickness are assumed to vary according to the volume distribu...