To investigate a cognitive diathesis-stress model, the present study evaluated the main and interactive effects of anxiety sensitivity (AS) and exposure to aversive conditions (past month) in predicting theoretically relevant panic vulnerability variables in an epidemiologically defined sample from Russia (N = 390). Consistent with expectation, findings suggested that the combination of high le...

Increased levels of oxidative stress (OS) in the brain have been linked to the etiology of several neurodegenerative diseases, e.g., Alzheimer’s and Parkinson’s disease (Navarro and Boveris, 2009; Melo et al., 2011; Radak et al., 2011; Sultana et al., 2013). A possible cause of increased OS levels is an imbalance in the omega-6 (n-6) and omega-3 (n-3) polyunsaturated fatty acids (PUFAs) (Kiecol...

The acutephase response (APR) is a systemic response to severe trauma, infection, and cancer, although many of the numerous cytokine-mediated components of the APR are incompletely understood. Some of these components, such as fever, reduced availability of iron and zinc, and nutritional restriction due to anorexia, appear to be stressors capable of causing harm to both the pathogen and the hos...

Both morbidity and mortality are consistently reported to be higher in males than in females in early life, but no explanation for these findings has been offered. This paper argues that the sex difference in early vulnerability can be attributed to the natural selection of optimal maternal strategies for maximizing lifetime reproductive success, as modelled previously by Trivers and Willard. T...

doi: 10.1111/j.1399-3054.2006.00644.x Previous studies indicate that conifers are vulnerable to cavitation induced by drought but in many cases, not by freezing. Rarely have vulnerability to drought and freezing stress been studied together, even though both influence plant physiology and the abundance and distribution of plants in many regions of the world. We studied vulnerability to droughta...

this study is focused on developing an integrated optimization-simulation based genetic algorithm model (iosga) to develop the operational policies for a multi-purpose reservoir system. the objective function of the optimization model is considered to be a linear function of reliability (rel), resiliency (res), and vulnerability (vul) of the river-reservoir system. genetic algorithm (ga) is emp...

The effect of life stress on depression is moderated by a repeat length variation in the transcriptional control region of the serotonin transporter gene, which renders carriers of the short variant vulnerable for depression. We investigated the underlying neural mechanisms of these epigenetic processes in individuals with no history of psychopathology by using multimodal magnetic resonance-bas...