Heparan sulphate (HS) is an abundant component of cell surfaces and the extracellular matrix. It binds to a wide variety of peptide growth factors, morphogens, chemokines and extracellular matrix proteins (e.g. fibronectin) and many of these interactions are essential for these effector proteins to transduce signals across the plasma membrane. The unique molecular design and flexibility of HS a...

kefiran is an exopolysaccharide produced by microorganisms present in the kefir grains that has several health promoting properties. in this research, physico-mechanical and thermal characteristics of nanocomposite film composed of kefiran-montmorillonite (mmt; 1, 3 and 5% w/w) were studied. results showed that the thickness and the tensile strength of the films increased by increasing the nano...

The world economic image has been changing. It has been a long time since the sole important resources of an organization were financial and physical. In the newly-emerged global economy, knowledge and information are accounted as the most significant resources in order to produce value. Obviously, as the demand for knowledge to reach success is increasing day by day, maintenance and enhancemen...

Background: Adolescence is a developmental period when adverse childhood experiences have a significant impact due to the changes in brain structure and functioning during this period. This research aimed to investigate the relationship between maltreatment and emotion regulation with moderating role of cognitive flexibility in adolescence with childhood trauma. Methods: This study was a desc...

This paper presents a new model updating approach for structural damage localization and quantification. Based on the Modal Assurance Criterion (MAC), a new damage-sensitive cost function is introduced by employing the main diagonal and anti-diagonal members of the calculated Generalized Flexibility Matrix (GFM) for the monitored structure and its analytical model. Then, ...

The structure at in nity of a matrix pencil can be obtained by rank determination of Toeplitz matrices. We show that the generic rank of these matrices equals the structural rank. Thus the Toeplitz matrix approach is also suited for investigations of structure matrix pencils. Computational results underline the e ciency of this approach.

Reconfigurable intelligent surfaces (RIS) have been actively researched as a potential technique for future wireless communications, which intelligently ameliorate the signal propagation environment. In conventional design, each RIS element configures and reflects its received independently of all other elements, results in diagonal phase shift matrix. By contrast, we propose novel architecture...

Motivation. To assist efforts in determining and exploring the functional properties of proteins, it is desirable to characterize and predict protein flexibilities. Results. In this study, the conformational entropy is used as an indicator of the protein flexibility. We first explore whether the conformational change can capture the protein flexibility. The well-defined decoy structures are con...

The interest in the influence of videogame experience on our daily life is constantly growing. "First Person Shooter" (FPS) games require players to develop a flexible mindset to rapidly react to fast moving visual and auditory stimuli, and to switch back and forth between different subtasks. This study investigated whether and to which degree experience with such videogames generalizes to othe...

While brain research shows great potential for advancing critical national security interests, the products of the laboratory cannot be realized in operational practice without the polishing and maturing demanded by federal science and technology (S&T) acquisition processes, particularly those of the Department of Defense. Although many acquisition planning functions are relatively conventional...