Four new myelographic agents, metrizamide, iopamidol, iohexol, and iotrol, were studied in the subarachnoid space of cynomolgus monkeys. Plain films and computed tomographic scans documented the transport of each material throughout the space and into the brain. At the concentration used (300 mg I/ml), all gave good radiopacity for myelography and delineation of the cerebral subarachnoid space....

Hydrocephalus is a neurological disorder that usually results from obstruction of the cerebrospinal fluid outflow in the ventricles or in the subarachnoid space. Magnetic resonance imaging offers a great deal of information to specialists in the clinical diagnosis and treatment processes of hydrocephalus. Recently we have proposed a new magnetic resonance imaging sequence that significantly hig...

Magnetic resonance image-based computerized segmentation was used to measure the volumes of the brain, gray and white matter components, and to identify regions with prolonged enhancement on T2-weighted imaging, such as periventricular or deep white matter hyperintensities. The authors also determined the volumes of the ventricles and subarachnoid space in control subjects and in patients with:...

Adenosine is an endogenous hypnotic molecule. However, the mechanism by which the level of extracellular adenosine is regulated remains to be elucidated. We found by Northern hybridization and enzyme assay that ecto-5(')-nucleotidase and adenosine deaminase (ADA), major enzymes responsible for the production and degradation of adenosine, respectively, were localized most abundantly in the lepto...

BACKGROUND Vasospasm is a serious complication associated with subarachnoid hemorrhage. Successful management of vasospasm will ultimately depend on a clear understanding of the scope of this phenomenon, including whether arterial elements of different calibers are equally affected. We therefore examined the responses to subarachnoid hemorrhage in rabbit basilar arteries, small pial arteries, a...

While the in vitro reactivity of cerebral conducting vessels following subarachnoid hemorrhage has been extensively studied, in vivo cerebrovascular CO2 reactivity has not been systematically investigated. We tested the hypothesis that, in the canine model of subarachnoid hemorrhage, the rise in cerebral blood flow normally seen with hypercapnia is blunted during delayed vasospasm. Four groups ...

We reported a case report of 50-year-old woman with stroke hemorrhage due to subarachnoid hypertensive urgency, left ventricular hypertrophy, and dyslipidemia. Subarachnoid indicates the presence blood in space between pia mater arachnoid which usually results from ruptured cerebral aneurysm or arteriovenous malformation. The patient presents decreased consciousness preceded by severe headache ...