OBJECTIVE We previously reported a statistically significant association of SCARB1 intronic single nucleotide polymorphism (SNP) rs10846744 with common carotid intimal-medial artery thickness in each of the 4 Multi-Ethnic Study of Atherosclerosis racial/ethnic groups (white, Chinese, black, and Hispanic). METHODS AND RESULTS Using an expanded sample of 7936 Multi-Ethnic Study of Atheroscleros...

BACKGROUND Noninvasive measures of arterial compliance may be useful for the detection of subclinical atherosclerosis. METHODS AND RESULTS Measures of calf and thigh arterial compliance (MaxV50) were recorded in 267 subjects who also underwent MRI of the distal aorta to quantify distal aorta atherosclerosis. The average of calf and thigh MaxV50 was strongly predictive of extent of aortic athe...

Cardiovascular disease (CVD) remains the main cause of death in diabetic patients, and once it has developed, diabetic patients have a worse outcome as compared with non-diabetic patients. One reason for this is the difficulty of early diagnosis of atherosclerotic change in these patients. Although cardiovascular risk assessment based on conventional risk factors is recommended for predicting c...

Abstract Introduction Sleep duration is associated with stroke risk and one of eight essential components cardiovascular health according to the American Heart Association. As disproportionately burdens Black Hispanic populations in United States, we hypothesized that long short sleep would be greater subclinical carotid atherosclerosis, a precursor stroke, racially ethnically diverse Northern ...