We introduce the problem of robust subgroup discovery, i.e., finding a set interpretable descriptions subsets that 1) stand out with respect to one or more target attributes, 2) are statistically robust, and 3) non-redundant. Many attempts have been made mine either locally subgroups tackle pattern explosion, but we first address both challenges at same time from global modelling perspective. F...

we examine the symplectic group $sp_{2m}(q)$ and its correspondingaffine subgroup. we construct the affine subgroup and show that itis a split extension. as an illustration of the above we study theaffine subgroup $2^5{:}sp_4(2)$ of the group $sp_6(2)$.

SEE PAGE 28 C ardiovascular drugs and devices may have different safety and efficacy profiles in certain populations. Performance of separate trials or subgroup analysis is important if there is a biological reason, either intrinsic and/or extrinsic, for a varied response to a therapy. For example, compared with men, women have different body size, hormonal milieu, sex-specific physiology, and ...

This was a secondary analysis of a randomized, placebo controlled trial of amoxicillin for acute LRTI in 16 primary research networks in 12 European countries from October 2007 until April 2010. More details on this GRACE-10 study (Genomics to combat Resistance against Antibiotics in Community-acquired LRTI in Europe, www.gracelrti.org) have been reported elsewhere [6]. Eligible patients were a...

Statin therapy in patients with cardiovascular disease is associated with reduced incidence of stroke. The Stroke Prevention by Aggressive Reduction of Cholesterol Levels (SPARCL) trial showed daily treatment with 80 mg of atorvastatin in patients with a recent stroke or transient ischemic attack (TIA) reduced the incidence of fatal or nonfatal stroke by 16%. Several post hoc analyses of differ...

To study genetic variation and molecular epidemiology of the G protein of respiratory syncytial virus (RSV), 253 strains from a children's hospital in Korea over 9 consecutive epidemics were analyzed. Restriction analysis of the entire G protein gene demonstrated 24 genotypes among 188 subgroup A and 6 among 65 subgroup B isolates. Two to 4 dominant genotypes of subgroup A cocirculated, and dif...

The discovery of (interesting) subgroups has a high practical relevance in all domains of science or business. For example, consider statements such as: ”the unemployment rate is above average for young men with a low educational level”, ”smokers with a positive family history are at a significantly higher risk for coronary heart disease”, or ”single males living in rural areas do rarely take o...

This paper presents a method that uses gene ontologies, together with the paradigm of relational subgroup discovery, to help find description of groups of genes differentially expressed in specific cancers. The descriptions are represented by means of relational features, extracted from gene ontology information, and are straightforwardly interpretable by the medical experts. We applied the pro...