The present study was carried out to investigate the structure of the sublingual caruncles of the goat. Specimens were studied by gross anatomy, morphometery, light and scanning electron microscopy. Results show that the sublingual floor of the oral cavity consisted of a rostral prefrenular part and two lateral sublingual recesses. The sublingual caruncles had a rostrolaterally directed serrate...

Many patients especially children and elderly have difficulty in swallowing tablets and capsules and consequently unable to take medicine as prescribed. Almost 50% of the population is affected by such problem, resulting in the high incidence of non compliance and ineffective therapy. Most pharmaceutical forms for oral administration are formulated for direct ingestion, or for chewing, or for p...

Tobacco smoking or nicotine administration on its own can influence cognitive task performance. This study examined the effects of acute nicotine administration on verbal task performance and a physiological index of arousal. Healthy non-smoking participants received either a 2 mg sublingual nicotine tablet or placebo. Participants next completed various verbal tasks while heart rate recordings...

Sublingual immunotherapy is gaining widespread attention as a viable alternative to subcutaneous immunotherapy for the treatment of allergic rhinoconjunctivitis. In addition, sublingual immunotherapy has been studied in other allergic disorders including asthma. However, a review of published studies indicates that there are deficiencies and considerable heterogeneity in both design and data in...

we want to compare the efficacy and safety of vaginal versus sublingual misoprostol for cervical ripening and induction of labor. this randomized clinical trial was performed on 140 women with medical or obstetric indications for labor induction. the patients were randomly divided into two groups: vaginal and sublingual administration of misoprostol. in first group, 25 µg misoprostol was placed...

Metastasis to the sublingual lymph nodes is very rare in oral cavity cancers. We present an early-stage floor of the mouth (FOM) cancer case with metastasis to the sublingual lymph node. Even though the rate of metastatic sublingual lymph nodes is low, the uncommon presence of sublingual lymph node metastasis in an early-stage FOM cancer case raises the question of routine FOM dissection. Furth...

Background: Opioid use disorder is a major concern to public health, and opioid maintenance treatment onmethadone or buprenorphine is a widely used approach. On the other hand, in recent years, there has beenmore regards for the use of opium tincture for detoxification and maintenance treatment of opioiddependence in certain parts...

The demand of fast disintegrating tablets has been growing during the last decade, due to the characteristics of fast disintegrating sublingual tablets for the potential emergency treatment. In terms of permeability, the sublingual area of the oral cavity (i.e, the floor of the mouth) is more permeable than the buccal (cheek) area, which in turn is more permeable than the palatal (roof) of the ...