The therapeutic management of symptomatic uterine fibroids is based on three pillars: surgery, pharmacotherapy, and interventional radiotherapy. Modern myoma treatment is personalised and should involve an interdisciplinary approach according to the patient’s wishes and pathology.

Hyperemesis gravidarum can cause various vitamin deficiencies. Vitamin K deficiency can lead to coagulopathy or hemorrhagic diathesis. A nulliparous Japanese woman with hyperemesis gravidarum at 10(5/7) weeks was admitted with giant myoma, intestinal obstruction, and abdominal pain. Treatment for a degenerative myoma was instituted with intravenous antibiotics. The abdominal pain ameliorated, b...

PROBLEM To explore the roles of leptin, monocyte chemotactic protein (MCP)-1, and tumour necrosis factor (TNF)-α in the peritoneal fluid (PF) in the pathogenesis of endometriosis-associated infertility. METHOD OF STUDY Leptin, MCP-1, and TNF-α levels in the PF from 28 infertile women with endometriosis (study group), 23 women with fallopian-associated infertility (controls), and 24 women with...

Leiomyomas are common benign uterine tumors. However, the incidence of vaginal myoma is very rare and may be confused with a variety of vaginal tumors. We report a case of 43-year-old nulligravida who presented with a protruding painful vaginal mass for 7 days. The mass had initially appeared 3 years prior, as 2 to 3 cm that had not subsequently increased. However suddenly, there was rapid seve...

background: according to age, history and physical examination findings, there are different diagnoses including anatomic lesions for abnormal uterine bleeding (aub). in these conditions, hysteroscopy can be performed as a diagnostic and therapeutic procedure. objective: the aim of this study was defining the diagnostic value of hysteroscopy in evaluating uterine cavity in patients with aub com...

background: in fertile women, glycodelin and glutathione peroxidase 3 (gpx3) genes expression rises during the luteal phase, with a peak occurring during the implantation window. the expression of these genes decreases in women with myomas. to determine whether myomectomy would reverse glycodelin and gpx3 expression, we evaluated the transcript levels of these genes in the endometrium of patien...

A 40 years old single woman was presented with severe abdominal pain, progressive in nature (acute abdominal) during clinical examination a huge abdominal mass arising from pelvis was found with signs of abdominal rigidity and guarding. All other clinical features were within normal range. The abdominal ultrasound examination revealed abdominopelvic mass, irregular in shape with some degenerati...