Our goal was to develop a method to identify the optimal elastic modulus, Poisson's ratio, porosity, and permeability values for a mechanically stressed bone substitute. We hypothesized that a porous bone substitute that favors the transport of nutriments, wastes, biochemical signals, and cells, while keeping the fluid-induced shear stress within a range that stimulates osteoblasts, would likel...

QUESTION In people with sciatica in primary care, can a single question be used to predict outcome at 1 year followup as accurately as validated questionnaires on kinesiophobia, disability, and health-related quality of life? DESIGN Observational study within a randomised cohort. PARTICIPANTS 135 people with sciatica in primary care. OUTCOME MEASURES Kinesiophobia was measured with the Ta...

Wounds with full-thickness skin loss are commonly managed by skin grafting. In the absence of a graft, reepithelialization is imperfect and leads to increased scar formation. Biomaterials can alter wound healing so that it produces more regenerative tissue and fewer scars. This current study use the new chitosan based biomaterial in full-thickness wound with impaired healing on rat model. Wound...

In this paper, we show a no-go theorem for static spherically symmetric black holes with vector hair in Einstein-$\Lambda$-Vector-Tensor-Gauss-Bonnet theory where complex field non-minimally couples Gauss-Bonnet invariant. For purpose, expand metric functions and radial of around the event horizon, substitute expansions into equations motion. Demanding that motion are satisfied each order, vani...