Within the last several years, the poultry industry has seen a dramatic increase in the occurrence of pale, soft, and exudative (PSE) meat. This problem is known to be associated with a rapid decline in postmortem (PM) muscle pH, which results in inferior protein functionality similar to that found in PSE pork. Many factors such as seasonal changes have been known to influence the occurrence of...

A randomized control trial was done between January and December of 2018, in the Department Anaesthesia, Analgesia, Palliative & Intensive Care Medicine Dhaka Medical College Hospital, Bangladesh, to evaluate preventive effect pregabalin on succinylcholine induced adverse effects, i.e., fasciculation, myalgia hyperkaliemia spine surgery. Sixty patients elective surgery under general anaesth...

OBJECTIVE To determine the effects of dexmedetomidine on the incidence of fasciculation and myalgia, and to evaluate changes in creatine kinase levels due to succinylcholine administration. METHODS Sixty patients undergoing direct laryngoscopy were enrolled in this study carried out in the Department of Anesthesiology and Reanimation, Hacettepe University, Ankara, Turkey between January and M...

We have compared rapacuronium 2.5 mg kg-1 (n = 20) with succinylcholine 1.5 mg kg-1 (n = 22) in a multicentre, blinded, randomized study in full-term parturients undergoing elective Caesarean section under general anaesthesia. Thiopental 5 mg kg-1 was given i.v. followed by the neuromuscular blocking agent. Sixty seconds later intubation was performed. Intubating conditions, evaluated as excell...

BACKGROUND Because of the rapid recovery of neuromuscular function after succinylcholine administration, there is a belief that patients will start breathing sufficiently rapidly to prevent significant oxygen desaturation. The authors tested whether this belief was valid. METHODS Twelve healthy volunteers aged 18-45 yr participated in the study. After preoxygenation to an end-tidal oxygen con...

The incidence of postoperative myalgia (POM) after succinylcholine administration has been reported to range from 5% to 83%. The administration of small doses of nondepolarizing muscle relaxants or lidocaine before the administration of succinylcholine has been shown to decrease the incidence and severity of POM experienced by patients. The purpose of this investigation was to compare the sever...

T he Clreat Paracelsus (Philipus Aureolus Theophrastus Bonihastus von Hohenheini-Paracelsus, 1493-1541) is remembered by toxicologists for his famous quote: "All substances are poisons; there is none which is not a poison. Tlie right dose differtntiates a poison from a remedy-"' Intieed, tiic l)iisic principle from the quotation still applies today. The right dose of morphine that will produce ...

Sugammadex 16 mg kg⁻¹ can be used for the immediate reversal of neuromuscular block 3 min after administration of rocuronium and could be used in place of succinylcholine for emergency intubation. We have systematically reviewed the efficacy and cost-effectiveness and made an economic assessment of sugammadex for immediate reversal. The economic assessment investigated whether sugammadex appear...

BACKGROUND AND OBJECTIVES Epidural action of neuromuscular blocking agents could be explained under the light of their physicochemical characteristics and epidural space properties. In the literature there are few cases of accidental neuromuscular agent's epidural administration, manifesting mainly with neuromuscular blockade institution or fasciculations. CASE REPORT We report a case of acci...