Wheat is an important source of proteins and metabolites for human and animal nutrition. To assess the nutritional quality of wheat products, various protein and diverse metabolites have to be evaluated. The grain storage protein family of the α-gliadins are suggested to be the primary initiator of the inflammatory response to gluten in Celiac disease patients. With the technique of RNAi, the α...

This study was designed to determine the toxic effects of nickel sulfate on the biochemical and elemental profile of liver in protein deficient rats. Nickel sulfate in the dose of 800mg/l in drinking water was administrated to Sprauge Dawley (S.D) normal control as well as protein deficient rats for a total duration of eight weeks. The effects of nickel treatment and protein deficiency when giv...

Heparan sulfate proteoglycans (HSPG) are obligatory for receptor binding and mitogenic activity of basic fibroblast growth factor (bFGF). The capacity of various species of heparin and heparan sulfate (HS) to promote bFGF receptor binding was investigated using both Chinese hamster ovary mutant cells deficient in cell surface HSPG and a soluble bFGF receptor-alkaline phosphatase fusion protein....

When the pressure leaching process of chalcopyrite is operated in low and medium temperature range 90℃~150℃, sulfur component converted to elemental sulfur, which suppresses copper. In present study, copper rate was improved by adding chloride ions surfactants during medium-temperature at 150℃. Using autoclave equipped with a 2L reactor made titanium, leach tests were conducted for 180 min usin...

Although environmental stimuli are known to affect the structure and function of microbial communities, their impact on the metabolic network of microorganisms has not been well investigated. Here, geochemical analyses, high-throughput sequencing of 16S rRNA genes and transcripts, and isolation of potentially relevant bacteria were carried out to elucidate the anaerobic respiration processes st...

The metabolism of certain inorganic forms of sulfur by various autotropic bacteria has been studied extensively in the past. However, investigations dealing with the metabolism of sulfur compounds by the heterotropic bacteria have not been numerous. Such work as has been done (reviewed by Meyers and Porter (1)) indicates that these microbial systems may be quite specific in their requirements f...

Ornithine decarboxylase (ODC) catalyses the conversion of ornithine to putrescine, an obligate precursor to the polyamines spermidine and spermine. We reported previously that homozygous odc-1 (pc13) worms have no detectable ODC activity. Despite their inability to make polyamines, these mutant worms appear normal, but with a slight reduction in total brood size, when grown in complex medium th...

Regulation of low density lipoprotein (LDL) receptor activity of cultured human skin fibroblasts was studied by measuring 4 degrees C binding of 125I-LDL after cells were incubated at 37 degrees C with medium containing varying lipoprotein and serum compositions. When cells grown on medium containing 10% human whole serum were exposed to medium containing 10% human lipoprotein-deficient serum, ...

Small peptides (2-5 amino acid residues) are transported into Saccharomyces cerevisiae via two transport systems: PTR (Peptide TRansport) for di-/tripeptides and OPT (OligoPeptide Transport) for oligopeptides of 4-5 amino acids in length. Although regulation of the PTR system has been studied in some detail, neither the regulation of the OPT family nor the environmental conditions under which f...

The product of an episulfonium ion-mediated cyclotrimerisation, previously reported as being a 15-membered ring trilactam, has now been shown to be a 1,3,5-triazine. Smaller medium-ring bilactams have, however, been synthesised from linear precursors using the sulfur-based methodology.