A strain of Klebsiella aerogenes is described which was unable to grow from light inocula on 5% lysed horse blood diagnostic sensitivity test (DST) agar. It was able to grow on DST agar without added horse cells and MacConkey and nutrient agar. Growth on a deficient medium was promoted by sulphonamides and nitrofurantoin as well as by para-amino benzoic acid, para-amino salicylic acid, procaine...

TRACHOMA is a widely prevalent disease in India and one of the most common causes of blindness. The idea that the disease is due to a virus is supported by the presence of intracellular inclusion bodies. Since the advent of sulphonamides and antibiotics many workers have used them in an attempt to cure trachoma, and opinion is sharply divided as to their merits. In this series of cases the valu...

OBJECTIVES A florfenicol-resistant Pasteurella trehalosi isolate from a calf was investigated for the presence and the location of the gene floR. METHODS The P. trehalosi isolate 13698 was investigated for its in vitro susceptibility to antimicrobial agents and its plasmid content. A 14.9 kb plasmid, designated pCCK13698, was identified by transformation into Pasteurella multocida to mediate ...

In a retrospective study to compare the drug consumption during pregnancy of mothers of infants with congenital abnormalities and of those without, over 97% of 1,369 mothers took prescribed drugs and 65% self-administered drugs. Significantly more mothers of infants with congenital abnormalities took aspirin, antacids, dextroamphetamine, phenobarbitone, sodium amytal, other barbiturates, cough ...

A series of novel isatine-sulphonamide derivatives have been synthesized by combining isatin derivatives with sulphonamides. The structure of the synthesized compounds were elucidated by spectral analysis (IR, NMR and Mass). Investigation of anti-HIV activity was done against HIV-1(IIIB) in MT-4 cells and HIV integrase inhibitory activity. 4-(1-acetyl-5-methyl-2-oxoindolin-3-ylideneamino)-N-(4,...

Laboratory, Colindale, London) The traveller newly arrived at his destination, particularly if a warm climate, is commonly affected by acute diarrhoea within 14 days, a condition usually referred to as 'traveller's diarrhoea'. In 1965 a bacteriological study was made on 540 men belonging to an Army unit which moved by air from the United Kingdom to Aden. Cases of diarrhoea commenced about four ...