نتایج جستجو برای: superantigen

تعداد نتایج: 1446  

Journal: :The Journal of Experimental Medicine 1996
L Liao A Marinescu A Molano C Ciurli R P Sekaly J D Fraser A Popowicz D N Posnett

Both superantigens (SAG) and many anti-TCR monoclonal antibodies (mAb) have specificity for the V beta region of the TCR encoded by TCRBV genes. For instance the bacterial SAG staphylococcal enterotoxin E (SEE), the retroviral SAG MTV-9 and the mAb OT145 each react with human T cells expressing BV6S7. This BV gene encodes two common alleles. We found that SEE and the mAb preferentially activate...

Journal: :Zoonoses 2022

Since the International Health Regulations National Focal Point for United Kingdom alerted WHO of ten cases acute severe hepatitis unknown etiology in children on April 5, 2022, relevant have been reported worldwide. These patients had (negative viruses A–E) and elevated aminotransferase (AST) or alanine aminase (ALT) exceeding 500 U/L. Furthermore, respiratory syndrome coronavirus type 2 (SARS...

Journal: :Infection and immunity 2005
Teresa Krakauer Stephen F Little Bradley G Stiles

Various in vitro effects of staphylococcal enterotoxin B (SEB) on human peripheral blood mononuclear cells were mitigated by Bacillus anthracis edema toxin. In particular, levels of some SEB-induced cytokines (tumor necrosis factor alpha, gamma interferon) and chemokines (monocyte chemoattractant protein 1, macrophage inflammatory protein 1 alpha [MIP-1alpha], MIP-1beta) were significantly dimi...

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