نتایج جستجو برای: superoxide dismutases

تعداد نتایج: 33659  

2007
Milan Flekac Jan Skrha Jirina Hilgertova Zdena Lacinova Marcela Jarolimkova

Background: Reactive oxygen species generated by hyperglycemia modify structure and function of lipids, proteins and other molecules taking part in chronic vascular changes in diabetes. Low activity of scavenger enzymes has been observed in diabetic patients and their protective role in oxidative stress may be deteriorated. This study was undertaken to investigate the association between polymo...

Journal: :Genetics 1994
P Chary D Dillon A L Schroeder D O Natvig

Enzymatic superoxide-dismutase activity is believed to be important in defense against the toxic effects of superoxide. Although superoxide dismutases are among the best studied proteins, numerous questions remain concerning the specific biological roles of the various superoxide-dismutase types. In part, this is because the proposed damaging effects of superoxide are manifold, ranging from ina...

Journal: :FEMS yeast research 2014
Patrícia Ferreira Teresa Cardoso Filipa Ferreira Manuel Fernandes-Ferreira Peter Piper Maria João Sousa

Mentha piperita (MP), also known as peppermint, is an aromatic and medicinal plant widely used in the food industry, perfumery and cosmetic, pharmacy and traditional medicine. Its essential oil (EO) displays antimicrobial activity against a range of bacteria and fungi. In this study, we found that MP EO lethal cytotoxicity is associated with increased levels of intracellular reactive oxygen spe...

Journal: :Carcinogenesis 2001
K Mitrunen P Sillanpää V Kataja M Eskelinen V M Kosma S Benhamou M Uusitupa A Hirvonen

Superoxide dismutases play a key role in the detoxification of superoxide radicals and thus protect cells from damage induced by free radicals. Within mitochondria manganese superoxide dismutase (MnSOD) provides a major defence against oxidative damage by reactive oxygen species. Polymorphism in the mitochondrial targeting sequence of MnSOD has recently been associated with risk of breast cance...

Journal: :Acta Crystallographica Section F Structural Biology and Crystallization Communications 2006

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