Deoxyribonucleic acid double-stranded breaks act as intermediates in Ig V(D)J recombination and probably perform a similar function in class switch recombination between IgH C genes. In SCID mice, V(D)J recombination is blocked because the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) protein is defective. We show in this study that switching to all isotypes examined was detectable ...

Sensorineural hearing loss is associated with increased temporal masking of low energy sub-segments of speech by adjacent high energy segments, resulting in increased consonant confusion. Splitting the speech into segments and presenting the alternate segments to the two ears, may help in reducing the effect of increased temporal masking in cases of moderate bilateral loss. A method of inter-au...

Finding minimum cost switching function is an intractable problem. The number of prime implicant of a typical switching function is the order of 3 [5][13]. When fitness function with respect to cost is the only goal, the existing algorithms require faces combinatorial explosion [20]. The allurement of approximation and heuristic algorithms in this area has already generated ESPRESSO algorithm. ...

In this paper, a novel approach based on the Thévenin tracing is presented to modified conventional impedance-based out-of-step (OOS) protection. In conventional approach, the OOS detection is done by measuring positive sequence impedance. However, the measured impedance may be change due to different factors such as capacitor bank switching and reactive power compensators that it can cause the...

The paper presents a new method for higher order sliding mode control using control Lyapunov function for chain of integrator system with nonlinear uncertainties. The stability proof of the suggested scheme is analyzed in terms of two Lyapunov functions using appropriate switching function. Using these Lyapunov functions and switching scheme it is proved that, output and its higher order deriva...

The optimal reward function associated with the so-called "multiarmed bandit problem" for general Markov-Feller processes is considered. It is shown that this optimal reward function has a simple expression (product form) in terms of individual stopping problems, without any smoothness properties of the optimal reward function neither for the global problem nor for the individual stopping probl...

A major problem in an isolated DC/DC converters operating at high switching frequencies is the attendant switching losses in the semiconductor devices. This can be reduced by introducing either zero-voltage switching (ZVS) or zero-current switching (ZCS) of the semiconductor switches. This paper deals with the simulation, design, fabrication and experimental evaluation of a novel soft-switching...