نتایج جستجو برای: synaptic terminal

تعداد نتایج: 207353  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2005
Hideki Takago Yukihiro Nakamura Tomoyuki Takahashi

The alpha-amino-3-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is an ionotropic receptor mediating excitatory synaptic transmission, but it can also interact with intracellular messengers. Here we report that, at the calyx of Held in the rat auditory brainstem, activation of AMPARs induced inward currents in the nerve terminal and inhibited presynaptic Ca2+ currents (I(pCa)), thereby att...

2012
Natalia López-del Hoyo Lucrezia Fazioli Santiago López-Begines Laura Fernández-Sánchez Nicolás Cuenca Jordi Llorens Pedro de la Villa Ana Méndez

Guanylate cyclase activating proteins are EF-hand containing proteins that confer calcium sensitivity to retinal guanylate cyclase at the outer segment discs of photoreceptor cells. By making the rate of cGMP synthesis dependent on the free intracellular calcium levels set by illumination, GCAPs play a fundamental role in the recovery of the light response and light adaptation. The main isoform...

Journal: :Journal of cell science 1998
W Haubensak F Narz R Heumann V Lessmann

The protein family of mammalian neurotrophins, comprising nerve-growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 and -4/5 (NT-3, NT-4/5), supports the survival and the phenotype of neurons from the central as well as the peripheral nervous system (CNS, PNS). In addition, exogenous application of neurotrophins has recently been found to modulate synaptic transmission...

Journal: :Science China. Materials 2022

Brain-like computing is an important direction for the development of integrated circuits in post-Moore era, and artificial synaptic devices that can simulate ideal behavior key to building brainlike chips with neuron-synapse-neuron connectivity. Ferroelectric thin film materials have unique nonvolatile polarization, plasticity polarization very similar biological synapses, so ferroelectric bee...

2017
So Young Park So Young Jang Yoon Kyoung Shin Dong Keun Jung Byeol A Yoon Jong Kook Kim Young Rae Jo Hye Jeong Lee Hwan Tae Park

The vertebrate neuromuscular junction (NMJ) is considered as a "tripartite synapse" consisting of a motor axon terminal, a muscle endplate, and terminal Schwann cells that envelope the motor axon terminal. The neuregulin 1 (NRG1)-ErbB2 signaling pathway plays an important role in the development of the NMJ. We previously showed that Grb2-associated binder 1 (Gab1), a scaffolding mediator of rec...

Journal: :مجله علوم اعصاب شفای خاتم 0
niloofar rambod rad islamic azad university, mashhad branch, mashhad, iran alma miraghel islamic azad university, mashhad branch, mashhad, iran mohammad reza khojaste islamic azad university, mashhad branch, mashhad, iran

neuroplasticity is the brain's ability to reorganize itself by forming new neural connections throughout life. neuroplasticity allows the neurons in the brain to compensate injury and disease and to adjust their activities in response to new situations or to changes in their environment. at the other side, it is now well established that neuronal function is strongly influenced by both cen...

پایان نامه :0 1381

1-میزان فراوانی انواع اکلوژن به ترتیب نزولی به صورت مال اکلوژن ‏‎cl i-cl ii‎‏ -نرمال-‏‎cl iii-flush terminal plane-mesial step‎‏ و ‏‎distal step‎‏ مشاهده گردید.2-میزان فراوانی اکلوژن نرمال و مال اکلوژن ‏‎cl iii‎‏ و ‏‎flush terminal plane‎‏ در پسرها نسبه به دخترها و مال اکلوژنهای ‏‎cl iii,cli‎‏ و ‏‎mesial step‎‏ و ‏‎distal step‎‏ و در دخترها نسبت به پسرها بیشتر است.3-به غیر از کودکان 6ساله که ما...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2000
R Fernández-Chacón T C Südhof

In vertebrates, secretory carrier membrane proteins (SCAMPs) 1-3 constitute a family of putative membrane-trafficking proteins composed of cytoplasmic N-terminal sequences with NPF repeats, four central transmembrane regions (TMRs), and a cytoplasmic tail. SCAMPs probably function in endocytosis by recruiting EH-domain proteins to the N-terminal NPF repeats but may have additional functions med...

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