PURPOSE The aim of this study was to investigate the prognosis, patterns of failure, and prognostic factors for breast cancer patients with pathologically proven synchronous ipsilateral supraclavicular lymph node (ISCLN) metastases. METHODS We reviewed the records of breast cancer patients with pathologically proven ISCLN metastases. Local aggressive treatment was defined as treatment includi...

objective(s): breast cancer is the most common type of cancer among women worldwide. this study investigated the expression and clinical significance of activating transcription factor 3 (atf3) in human breast cancer and its relationship with the clinical outcome of breast cancer.   materials and methods : atf3 expressions were detected in 114 primary breast cancer tissues and 114 adjacent norm...

ever since psychological issues became a focus of attention in oncology, many studies have been conducted to quantitatively address the impaired sexual function among women diagnosed with breast cancer; however, we lack qualitative measurement of sexual dysfunction and patients’ needs. conducting research about “sexual function in breast cancer patients” in 2009 at the tehran cancer institute s...

background : breast cancer is a complicated disease and has various clinical manifestations and prognosis. the aim of this study is to make a breast cancer model suitable for basic, preclinical and clinical studies. materials and methods: five virgin bulb/c mice aged 6 weeks and spontaneous murine mammary adenocarcinoma cells (mmac) were used. after anesthesia induction, 1-3 million of mmacs we...

background: emotional intelligence (eq) is positively associated with mental health and it can have a crucial role in mental disorder therapy by suitable coping mechanisms. the present study aimed to evaluate the relationship of eq with anxiety and depression among the women with breast cancer. subjects and methods: during 2013 and in a cross-sectional study, 98 breast cancer patients (14 to 21...

recent studies have indicated the profound  anti-tumor activity of artemisinin's compounds,  among  which;  arteether  is an  oil-soluble derivative of  artemisinin with an endoperoxide bridge that can induce apoptosis in tumor cells but not in the normal cells. an experiment was carried out on tumor-bearing balb/c mice to estimate the effects of arteether  on  tumor  growth  and  antitumor  im...

treatment related acute myeloid leukemia (t-aml) is well documented phenomenon after chemotherapy. in this subgroup of patients acute promyelocytic leukemia (apml) due to delayed complication of using anthracycline is very rare occurrence. very few cases are reported in world literature. we are reporting a rare case of occurrence of t-apml in cured breast cancer patient treated with doxorubicin...

conclusions exercise can improve anthropometric variables, body composition and vo2 peak and reduce some inflammatory markers in breast cancer survivors. objectives the current study aimed to investigate the effect of eight weeks of training on il-6, tnf-α and hcrp in postmenopausal breast cancer survivors. patients and methods twenty-seven postmenopausal breast cancer survivors with mean age o...

patients and methods in this qualitative study, 19 women with breast cancer were interviewed regarding their empowerment needs using the individual open-ended and, in-depth interviews and then the qualitative data were analyzed through content analysis. background due to the increasing number of women suffering from breast cancer worldwide, promoting the empowerment of these patients is an impo...