Number of tumours (papillomas) produced by the application of 7,12-dimethyl benz (a) anthracene as initiator and croton oil promoter in mice were considerably inhibited (84%) by the prior application of eugenol. Moreover, there was considerable decrease in the number of tumour bearing animals and their onset. Eugenol inhibited superoxide formation and lipid peroxidation and the radical scavengi...

Abstract Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae) is one of the most destructive pests stored products. Although there have been studies on potential use essential oils from plants in Artemisia genus as insecticides, no comprehensive bioactivity data are available efficacy vulgaris L. (Asterales: Asteraceae) oil and its chemical constituents stored-product pests. Therefore, this...

introduction: pulpectomy is a conservative treatment plan for primary necrotic teeth and zinc oxide eugenol is still a good choice as root canal filling material but long term studies on poor prognosis molars are limited and almost contradictory. the purpose of this study is to evaluate the clinical and radiographical success rate of pulpectomy of necrotic primary molars using zoe as the root c...

introduction: intrinsic tooth discolorations after endodontic treatment are principally attributed to the composition of necrotic pulp tissue, hemorrhage within the pulp cavity, endodontic medicaments and/or filling materials. residual sealer left in pulp chamber after obturation can cause discoloration. the objective of this in vitro study was to evaluate coronal discoloration created by ah26 ...

objective: the immunomodulatory effect of geranial, geranial acetate, gingerol, and eugenol essential oils were evaluated by studying humoral and cell-mediated immune responses. materials and method: the essential oils were evaluated for immunomodulatory activity in in vivo studies, using rats as the animal model. the essential oils were tested for hypersensitivity and hemagglutination reaction...

objective(s): to investigate the effect of cinnamaldehyde and eugenol on the telomere-dependent senescence of stem cells. in addition, to search the probable targets of mentioned phytochemicals between human telomere interacting proteins (tips) using in silico studies. materials and methods: human adipose derived stem cells (hascs) were studied under treatments with 2.5 µm/ml cinnamaldehyde, 0....

We investigated the evidence of gastric protection for ulcer and gastritis by Cinnamomi Ramulus (Cinnamomum cassia Blume, Geiji, CR) extract and its several constituents. CR ethanolic extract showed the potent antioxidant activity and cytotoxicity of Helicobacter pylori (H. pylori) and acid-neutralizing capacity. Especially, eugenol exerted a significant antioxidant activity and inhibited the c...

Eugenol is an essential oil mainly found in the buds and leaves of clove (Syzygium aromaticum (L.) Merrill and Perry), which has been reported to have activity on inhibition of cell proliferation and apoptosis induction in human MCF-7 breast cancer cells. This biological activity is correlated to its activity as an estrogen receptor antagonist. In this article, we present the construction and v...

Methyleugenol, the methyl ether of eugenol, both of which are flavorant constituents of spices, has been listed by the National Toxicology Program's Report on Carcinogens as reasonably anticipated to be a human carcinogen. This finding is based on the observation of increased incidence of malignant tumors at multiple tissue sites in experimental animals of different species. By contrast, eugeno...

PURPOSE The purpose of this study was to compare the in-vitro effects of a European-based formocresol formulation that incorporates eugenol with formocresol alone on the adhesion of macrophages to plastic surfaces. METHODS Macrophages were obtained from Wistar rats. The adherence capacity of macrophages to a plastic surface was determined. Assays were carried out in Eppendorf tubes incubated ...