Poor social health has been linked to risk of neuropsychiatric disorders. Neuroimaging studies have shown associations between and global white matter microstructural integrity. We aim identify which tracts are involved in these associations. Social markers (loneliness, perceived support, partnership status) integrity 15 (identified with probabilistic tractography after diffusion magnetic reson...

Abstract Lower Goru sand intervals of Early Cretaceous age are proven reservoirs in the Indus Platform area. The delineation reservoir geometries is utmost importance while searching for stratigraphic and combination traps clastic reservoirs. data ten wells two 2D seismic lines from northern part Basin incorporated this study. These Formation correlated a third-order sequence framework to under...

An expansion to >200 CGG/CCG repeats (hereafter called CGG) in the 5' region of the FMR1 gene causes fragile X syndrome, and this locus becomes a folate-sensitive fragile site. We used Saccharomyces cerevisiae as a model system to study the stability and fragility of CGG repeats. Tracts of (CGG)(81)and (CGG)(160)were integrated onto a yeast chromosome in both orientations relative to the neares...

The vitamin biotin is an endogenous molecule that acts as an important cofactor for several carboxylases in the citric acid cycle. Disorders of biotin metabolism produce neurological symptoms that range from ataxia to sensory loss, suggesting the presence of biotin in specific functional systems of the CNS. Although biotin has been described in some cells of nonmammalian nervous systems, the di...

Body dysmorphic disorder (BDD) is characterized by an often-delusional preoccupation with misperceived defects of appearance, causing significant distress and disability. Although previous studies have found functional abnormalities in visual processing, frontostriatal, and limbic systems, no study to date has investigated the microstructure of white matter connecting these systems in BDD. Part...

Klingler dissection [LK56] as well as general blunt [Hei95] dissection of brain white matter shows the fiber bundles in the embedding tissue structures. White matter fiber tractography from diffusion tensor imaging (DTI) is, in general, visualized as 3D lines or tubes together with 2D anatomical MR slices or surfaces. However, determining the exact location of the fiber tracts in their surround...

Progress in magnetic resonance imaging (MRI) now makes it possible to identify the major white matter tracts in the living human brain. These tracts are important because they carry many of the signals communicated between different brain regions. MRI methods coupled with biophysical modeling can measure the tissue properties and structural features of the tracts that impact our ability to thin...