Dental caries results from altered microbial community activity in disease compared to health. Caries advanced into dentin was compared with coronal caries and caries-free sites. Oral bacterial samples were obtained from young children, placed in RNAlater and stored frozen. mRNAwas purified and sequenced on an Illumina NextSeq 500 platform. Gene sequences were aligned against taxa in HOMD and g...

The advent of "Adhesive Dentistry" has simplified the guidelines for cavity preparation enormously. The design and extent of the current preparations are basically defined by the extent and shape of the caries lesion, potentially slightly extended by bevelling the cavity margins in order to meet the modern concept of minimally invasive dentistry. New caries excavation techniques have been intro...

Available evidence indicates that infants, for the most part, acquire their oral flora, in particular Streptococcus mutans, from their mothers. The purpose of this study was to explore the effect of rampant caries in rat dams on subsequent caries activity in their offspring. Rampant caries was induced by surgical desalivation of four dams, and subsequent infection with Streptococcus sobrinus 67...

Scardovia inopinata JCM 12537(T) was isolated from human dental caries. Here, we report the complete genome sequence of this organism. This paper is the first report to demonstrate the fully sequenced and completely annotated genome of an S. inopinata strain.

Prediction of dental caries in pre-school children. Caries Res 1993; 27: 424–430). In these two papers, I was able to show a lower level of dental caries and a higher level of being caries free among the group that were non-secretors. This fits in well with the findings in the study of Kárpati from 2014. This work was carried out on children aged 4–6 years and included deciduous and newly erupt...

BACKGROUND Candida albicans may have cariogenic potential but its role in caries etiology has not been established. The aim of this study was to determine candida albicans in supragingival dental plaque and infected dentine of cervical and proximal in early childhood caries (ECC). METHODS This cross-sectional study was carried out on 6o children aged 2-5 years, which were divided into 3 group...

AIM The objective of this study was to determine the association between DIAGNOdent laser and caries detector dye in detection of the remaining caries in restorative cavities. MATERIALS AND METHODS The sample consisted of 100 cavities prepared in patients referring to the Department of Restorative Dentistry of Mashhad Dental School. After confirming caries absence by tactile examination, the ...

Caries disease is multifactorial. Whether caries disease will be expressed and damage dental hard tissue is dependent on the patient's own unique make-up of pathogenic risk factors and protective factors. Objectives This manuscript will review the science of managing caries disease based on assessing caries risk. Methods The caries balance/imbalance model and a practical caries risk assessment ...