Jongkind, C.C.H. & O. Lachenaud (2022). Novelties in African Apocynaceae. Candollea 77: 17–51. In English, English and French abstracts. preparing the treatment of Apocynaceae for Flore du Gabon, a number taxonomic novelties were discovered. Ten new species are here described illustrated, nine which occur Gabon: Baissea atrobrunnea Lachenaud, Hunteria maasiorum Jongkind E. Bidault, Landolphia a...

Ethanolic extract of Tabernaemontana divaricata L. (TD) flowers were evaluated for analgesic and antiinflammatory effects on Wistar rat model. Analgesic and anti-inflammatory potential of TD flowers at doses of 125, 250 & 500 mg/kg was evaluated against the standard drug indomethacin at a dose of 20 mg/kg, p.o. Wistar rats of either sex of 6 numbers in each group was undertaken for study and ev...

Tabernaemontana catharinensis (Apocynaceae) has been popularly used by folk medicine because of its anti-inflammatory, analgesic, and antiophidic properties. This study aims to analyze the flavonoids composition of the hydroethanolic extract and of the ethyl acetate (EtOAc) and butanol (BuOH) fractions of T. catharinensis leaves, as well as to evaluate their anti-inflammatory activity using in ...

Six new indole alkaloids, viz., cononusine (1, a rare example of an iboga-pyrrolidone conjugate), ervaluteine (2), vincamajicine (3), tacamonidine (4), 6-oxoibogaine (5), and N(4)-chloromethylnorfluorocurarine chloride (6), and two new vobasinyl-iboga bisindole alkaloids, ervatensines A (7) and B (8), in addition to other known alkaloids, were isolated from the stem-bark extract of the Malayan ...

The present study is aimed to evaluate the hepatoprotective effects of leaves and flower extracts of ervatamia coronaria against CCl4 induced hepatic damage. The results indicated that both flower and leaves extract of ervatamia coronaria exhibited significant effect against CCl4 induced hepatic damage. We also observed the restoration of elevated levels liver marker enzymes includes SGOT,SGPT,...

BACKGROUND & OBJECTIVES Acetylcholinesterase inhibitors (AChE-Is) are used for the treatment of Alzheimer's disease (AD). These drugs including galanthamine have been shown to modulate synaptic activity in hippocampus and improve memory processes. Although Tabernaemontana divaricata extract (TDE) has been used as traditional medicine for various pharmacological effects, its effect in enhancing ...

Virtual Screening and Molecular Docking analysis for Tabernaemontana divaricata derived 66 Law Molecular Weight Compounds (LMW) was conducted and to identified and predicted novel molecules as a inhibitor of Streptococcus pneumonia. The investigation has revealed several compounds with optimum binding towards Penicillin-binding proteins, Sialidases, Aspartate betasemialdehide dehydrogenase cell...

Sir, A 46‐year‐old woman presented with hyperkeratotic eczema and painful fissuring of the thumb, forefinger and third finger of the right hand (her dominant hand) of several months duration [Figure 1a and b]. Her lesions used to subside with the application of topical corticosteroids, but would reappear on stopping them. Detailed questioning revealed that she was in the habit of plucking certa...

The present study was undertaken to evaluate anxiolytic activity of alcoholic flowers extract of Tabernaemontana divaricata (Linn) R.Br. (ALETD) by using mice. This plant contains carbohydrates, steroids, tannins, triterpenes, flavonoids, proteins, amino acids and glycosides. Anxiolytic effect of ALETD (100, 200 and 400 mg/kg) was studied and diazepam used as a standard drug by using following ...