This work was supported by the Stiftung Mainzer Herz and the Robert Müller Stiftung. Further support was provided by the Center for Translational Vascular Biology (CTVB), the German Center vor Cardiovascular Research (DZHK), and the Center for Thrombosis and Hemostasis (CTH). T.M. is PI oft he DZHK. C.M. is supported by the Deutsche Forschungsgemeinschaft (DFG; Heisenberg Programm and SFB 894),...

Methods A 38 years old man with diagnose of Takayasu arteritis was admitted to our hospital with chest pain. Echocardiography revealed severe aortic regurgitation + ascending aorta dilatation. Computed tomographic angiography showed ascending aorta was 44 mm. He was scheduled for elective cardiac operation. His medication was adjusted as Addison protocol for operation. Axillary artery cannulati...

OBJECTIVE To investigate the probable pathogenesis, clinical features, diagnosis, and therapy of patients with pulmonary hypertension (PH) in Takayasu arteritis (TA). METHODS A total of 48 patients with TA who had PH, 20 patients with TA who had pulmonary arterial involvement (PA) without PH, and 30 patients with idiopathic pulmonary arterial hypertension (IPAH) were enrolled in the study fro...

Authors list: Reiko Kobatake, Kazuya Doi, Yoshifumi Oki, Hanako Umehara, Hiromichi Kawano, Takayasu Kubo, Kazuhiro Tsuga Affiliation: Department of Advanced Prosthodontics, Hiroshima University Graduate School of Biomedical and Health Sciences Corresponding author: Kazuya Doi Address: Department of Advanced Prosthodontics, Hiroshima University Graduate School of Biomedical Sciences, 1-2-3, Kasu...

Transcatheter arterial chemoembolization (TACE) is widely performed for unresectable hepatocellular carcinoma [1-6]. Recent meta-analysis of previous randomized controlled trial data of TACE for hepatocellular carcinoma reported that TACE could improve the survival rate [3, 4]. Selective TACE should be performed if possible, in order to avoid toxicity to the surrounding non-cancerous hepatic pa...

Takayasu arteritis is a devastating vasculitis of the aorta and its major branches. The clinical manifestations in paediatric patients are less specific than in adults: in children the disease presents with fever, arthralgias and hypertension. Intramural inflammation results in narrowing of the blood vessel lumen and therefore hypoperfusion of the parenchyma. Conventional angiography is the gol...

Background In 2006 Ozen et al proposed new diagnostic criteria for the classification of childhood vasculitides. The aim of this retrospective study was to describe the incidence of Wegener's Granulomatosis (WG), Polyarteritis Nodosa (PAN) and Takayasu Arteritis (TA) in Denmark during the period of 1976–1998. Furthermore, we wanted to classify them according to the Chapel Hill Classification Cr...