Tamarindus indica has several folkloric uses in the treatment of various ailments. This study evaluated analgesic activity methanol leaf extract (MLETI) mice and Wistar rats. Acute toxicity studies were conducted using both modified method Lorke OECD 425 guidelines. The was tested acetic acid-induced writhing test, hot plate formalin-induced hind-paw licking. Glycosides, flavonoids, saponins, a...

BACKGROUND Low level of acetylcholine (ACh) is an important hallmark of Alzheimer's disease (AD), a common type of progressive neurodegenerative disorder. Effective treatment strategies rely mostly on either enhancing the cholinergic function of the brain by improving the level of ACh from being a breakdown by cholinesterase enzymes. Again atherothrombosis is major life-threatening cerebral dis...