AIM To test the short term efficacy and safety of an infrared warm compression device (IWCD, Eye Hot, Cept Co, Tokyo, Japan) as treatment for non-inflamed meibomian gland dysfunction (MGD). METHODS 37 subjects with non-inflamed obstructive MGD, with and without aqueous tear deficiency (ATD) dry eye, participated in a prospective non-comparative interventional case series. Symptom scores, face...

Administration of topical rebamipide increases the mucin level of tear film and improves the ocular surface in short break-up time type of dry eye. Lid wiper epitheliopathy (LWE) is a disorder of the marginal conjunctiva of the upper eyelid with dry eye symptoms. LWE may be related to mechanical forces during blinking resulting in inflammation of the ocular surface. Rebamipide also has various ...

BACKGROUND/AIM Recent studies have demonstrated that tear lipocalin (TL) and phospholipids have a crucial role in maintaining tear film stability. The level of TL in patients with meibomian gland dysfunction (MGD) was examined and these data were correlated with the severity of their clinical disorder. METHODS 12 patients with obstructive MGD, 12 patients with seborrhoeic MGD, and 12 age matc...

Chronic smoking has negative effects on the ocular surface; chronic smokers had lower Schirmer scores in the corneas [1], a higher degree of squamous metaplasia [2,3], a higher grade of lipid layer changes in tears [3], and lower tear film break-up time compared with non-smokers [1-4]. Smoking also affects tear secretion and protein components in tears [5,6]. Furthermore, cigarette smoking may ...

PURPOSE To describe a case series in which corneal fluorescein staining (CFS) development occurred in short break-up time (s-BUT) dry eyes after a short period during prolonged opening of the eye. METHODS The study was designed as a clinical case series. Ocular surface evaluations were performed on 13 individuals with s-BUT dry eye. Tear function examinations included Schirmer's test and BUT ...

Background/aim: Recent studies have demonstrated that tear lipocalin (TL) and phospholipids have a crucial role in maintaining tear film stability. The level of TL in patients with meibomian gland dysfunction (MGD) was examined and these data were correlated with the severity of their clinical disorder. Methods: 12 patients with obstructive MGD, 12 patients with seborrhoeic MGD, and 12 age matc...

We examine a fluid dynamic model for the evolution of a precorneal tear film that includes evaporation of the aqueous layer and a wetting corneal surface. Our model extends previous work on the break-up time for a post-blink tear film to include a more realistic model for evaporation. The evaporation model includes the effects of conjoining pressure and predicts the existence of an equilibrium ...

Purpose of the study was to find out the relation between HbA1c which is an useful indicator of long term glycemic control and the qualitative and quantitive activity of precorneal tear film with the help of Tear Film Break up Time(TBUT) and Schirmer’s test respectively.40 type 2 diabetic patients and 20 age and sex matched healthy controls undergone HbA1c level, TBUT estimation and Schirmer’s ...

Background. The efficacy of acupuncture in dry eye syndrome patients remains controversial. Methods. Pubmed, Ovid, Cochrane libraries, CNKI, Wanfang, and CQVIP databases were electronically searched until October 1, 2014. Outcomes including tear break-up time (BUT), Schirmer I test (SIT), and cornea fluorescein staining (CFS) were analyzed. A meta-analysis was performed using both fixed- and ra...

The purpose of this study was to compare the topical anti-inflammatory effects of the nonselective cyclooxygenase (COX) inhibitor, ketorolac, with the selective COX-2 inhibitor, nimesulide, in an animal model of dry eye in albino rabbits. All animals were examined by the Schirmer test, tear break-up time (TBUT) and fluorescein corneal staining test. Dry eye model showed significant reduction in...