BACKGROUND Chronic tendon injuries, also known as tendinopathies, are common among professional and recreational athletes. These injuries result in a significant amount of morbidity and health care expenditure, yet little is known about the molecular mechanisms leading to tendinopathy. METHODS We have used histological evaluation and molecular profiling to determine gene expression changes in...

Subacromial shoulder pain is commonly located to the top and lateral side of the shoulder. It is exaggerated by overhead activity and can be associated with night pain. It is usually associated with full passive range of movement of the glenohumeral joint. The pain originates from the subacromial space of the shoulder, an area made up of the rotator cuff tendons and the subacromial bursa. This ...

OBJECTIVE To describe the subjective pain and functional improvements of a patient with chronic Achilles tendinopathy following a treatment plan incorporating active and passive tissue warm-up, followed respectively by soft tissue mobilization utilizing both Graston Technique(®) and Active Release Techniques(®), eccentric exercise, and static stretching in combination with cryotherapy. BACKGR...

Both acute and chronic tendinopathy result in high morbidity, requiring management that is often lengthy and expensive. However, limited and conflicting scientific evidence surrounding current management options has presented a challenge when trying to identify the best treatment for tendinopathy. As a result of shortcomings of current treatments, response to available therapies is often poor, ...

Hip abductor tendinopathy encompasses a constellation of etiologies all of which present with the chief complaint of lateral hip pain. It is four times more common in women and is usually seen between the fourth and sixth decades of life [5,6]. Patients with osteoarthritis, iliotibial band tenderness, low back pain, and obesity are at an increased risk [7,8]. Hip abductor tendinopathy falls und...

The Achilles tendon, named after the legendary warrior and hero of Homer’s Iliad, is the strongest and thickest tendon in the human body. Despite this fact, Achilles tendinopathy is a common overuse injury, particularly in runners and other athletes. Kujala et al showed a 10-fold increase in Achilles injuries in runners compared with age-matched controls. Another study reported the incidence of...

Overuse Achilles tendinopathy is a common and challenging problem in sports medicine. Little is known about the etiology of this disorder, and the development of a good animal model for overuse tendinopathy is essential for advancing insight into the disease mechanisms. Our aim was to test a previously proposed rat model for Achilles tendon overuse. Ten adult male Sprague-Dawley rats ran on a t...

Abstract Neovascularization is frequently observed in Achilles tendinopathy. It remains unclear whether neovascularization has a positive or negative impact on the prognosis of tendinopathy, and treatment should include eradication influence neovessels. The purpose this scoping review was to investigate effect ultrasound-guided interventions Five different were identified, which are characteriz...

BACKGROUND Chronic painful insertional Achilles tendinopathy is seen in both physically active and non-active individuals. Painful eccentric training, where the patients load the Achilles tendon into full dorsiflexion, has shown good results in patients with mid-portion Achilles tendinosis. However, only 32% of patients with insertional Achilles tendinopathy had good clinical results with that ...

We evaluated the expression of several genes involved in tissue remodelling and bone development in patients with calcific tendinopathy of the rotator cuff. Biopsies from calcified and non-calcified areas were obtained from 10 patients (8 women and 2 men; average age: 55 years; range: 40-68) with calcific tendinopathy of the rotator cuff. To evaluate the expression of selected genes, RNA extrac...