Three different substituted thiazoles have been successfully synthesized from readily available propargylic alcohols. Various secondary propargylic alcohols or tertiary propargylic alcohols participated well in the reaction, providing the desired products in good yields. This method provides a flexible and rapid route to substituted thiazoles.

Alkyl iodides and tertiary silanes were successfully coupled with good functional group tolerance using a Pt(P(tBu)(3))(2)/(iPr)(2)EtN/CH(3)CN system. The utility of the methodology is demonstrated by the synthesis of silafluofen, a Si-containing insecticide.

Five OXA-48-producing Klebsiella pneumoniae were detected in a tertiary referral hospital in Ireland between March and June 2011. They were found in the clinical isolates of five cases that were inpatients on general surgical wards. None of the cases had received healthcare at a facility outside of Ireland in the previous 12 months. This is the first report of OXA-48-producing K. pneumoniae in ...

BACKGROUND Learning through practice is enhanced when clinical environments support registered nurses to teach students. AIM This paper assesses the contribution of a supervisor of clinical education (SCE) employed to assist registered nurses partner with students and facilitate their learning during the clinical practicum. DESIGN A record of the activities of the SCE; and a survey complete...

Palliative care services provide secondary and tertiary levels of palliative care, the interdisciplinary care of patients in which the goal is comfort and quality of life. Primary palliative care refers to the basic skills and competencies required of all physicians and other health care professionals. Secondary palliative care refers to the specialist clinicians and organizations that provide ...

BACKGROUND Vaccination against influenza has been suggested to induce relapses of ANCA-associated vasculitis but evidence is lacking. In this study, we assessed whether vaccination against influenza increases the occurrence of relapses in patients with ANCA-associated vasculitis. METHODS Two hundred and thirty consecutive patients with ANCA-associated vasculitis from our out-patient clinics o...

We studied the use of videoconferencing for the pre-operative patient-surgeon interaction. Subjects were recruited from otolaryngology patients undergoing surgery at a tertiary hospital. They were randomised to a conventional face-to-face interaction with their surgeon or a videoconference call via tablet computer. Afterwards, subjects and surgeons completed questionnaires about the experience....

OBJECTIVES Colonoscopy is one of the major procedures in gastroenterology. Since the procedure is operator dependant, Quality of each procedure is the main element of reliable outcome. One of the elements is the completion rate. Completion rate of endoscopy unit is a reliable measure to improve the quality of the procedure. METHODOLOGY We here reviewed retrospectively our endoscopy database f...

BACKGROUND In Australia's Northern Territory, most Aboriginal people primarily speak an Aboriginal language. Poor communication between healthcare providers and Aboriginal people results in adverse outcomes including death. This study aimed to identify remediable barriers to utilisation of Aboriginal Interpreter services at the Northern Territory's tertiary hospital, which currently manages ove...

BACKGROUND A previous study showed that calls received by our continuity clinic residents were similar to those in private practice. However, that study did not address the compliance of the parents to the advice given. OBJECTIVE To determine parents' compliance to after-hours telephone advice given by pediatric residents in a continuity clinic. DESIGN Advice given during initial telephone ...