2 CONTENTS 3 LIST OF ABBREVIATIONS 4 1 RATIONALE – BACKGROUND 5 2 OBJECTIVE 6 3 METHOD DESCRIPTION 6 4 PARTICIPANTS 8 4.1 Co-ordination of the validation study 8 4.2 Preparation and distributing of the test samples 8 4.3 Homogeneity tests 8 4.4 Measurements 8 4.5 Collation and statistical evaluation of results 9 5 TEST SAMPLES 9 5.1 Homogeneity study 10 6 THE VALIDATION STUDY 10 6.1 Design of t...

The ECVAM validation concept, which was defined at two validation workshops held in Amden (Switzerland) in 1990 and 1994, and which takes into account the essential elements of prevalidation and biostatistically defined prediction models, has been officially accepted by European Union (EU) Member States and by the Federal regulatory agencies of the USA and the OECD. The ECVAM validation concept...

TTCN (Tree and Tabular Combined Notation) is the standardized test notation for the description of OSI conformance tests. Since applicability of TTCN is restricted, work on the deenition of concurrent TTCN, an extended version of TTCN for the speciication of test cases for multi party testing, has been started a few years ago. In this paper we discuss diierent approaches for the deenition of an...

This paper describes a test-bed for verification and validation activities in KT-NeOSS (Korea Telecom New Operations Support System) development. In this paper, we show the test phases for performing verification and validation activities during the development and maintenance of KT-NeOSS. We describe the experiences and considerations in building the test-bed for the activities. With this test...

The inherent vagueness and ambiguity of non-monotonic reasoning makes it impossible to formulate detailed specifications to validate KBS performance by using traditional test-case-based approach. In this paper, we present a practical validation technique for non-monotonic KBSs, which utilizes automatically generated test cases instead. We show how such test cases and other useful validation kno...

16 Objectives: A future treatment for uncomplicated malaria will contain at least one 17 component that exerts a rapid rate of kill (RoK). We describe here the validation and 18 application of a simple, robust and rapid bioluminescence-based assay for the 19 determination of the initial RoK in intraerythrocytic asexual stages of Plasmodium 20

This paper deals with the very fundamentals of a socalled TURIN(] test methodology for expert system validation which was proposed by the first author (cf. (Knauf, Gonzalez, aatd Philippow 1997), e.g.). First, we survey several concepts of verification and validation. Our favoured concepts axe lucidly characterized by the words that verification guarantees to build the system right whereas vali...

This paper deals with the very fundamentals of a so-called \Turing Test Methodology" for expert system validation which was recently proposed by KGP97]. First, we survey several concepts of veri-cation and validation. Our favoured concepts are lucidly characterized by the words that veriication guarantees to build the system right whereas validation deals with building the right system. Next, w...

This study evaluated the accuracy of the Standardized Field Sobriety Test (SFST) Battery to assist officers in making arrest decisions for DWI at blood alcohol concentrations (BACs) below 0.10 percent. NHTSA's SFST battery was validated at 0.10 percent BAC in 1981. The trend to reduce statutory DWI limits to 0.08 percent BAC prompted this research project. The research was composed of several p...

We address the problem of determining what fraction of the training set should be reserved as development test set or validation set. We determine that the ratio of the validation set size over the training set size scales like the square root of two complexity parameters: the complexity of the second level of inference (minimizing the validation error) over the complexity of the rst level of i...