The reproductive-related studies, including genetic and genomic such as gonadal transcriptome analyses, have previously focused on the adult spotted scat, with little information juvenile fish. Transcriptomics is a powerful tool that allows for massive parallel analysis to identify differential expression patterns of gene holistically at particular stage in cell or tissue development. This stud...

Leydig cells of the adult mouse testis express at a detectable level three distinct glandular (tissue) kallikrein genes: mKlk21, mKlk24, and mKlk27. Recently, the proteins encoded by these genes were characterized using active recombinant proteases, but their roles in the mouse testis remained to be determined. The present study showed that among the proteases, mK24 markedly enhanced the activi...

by reduction in size of the testis through degenerative changes. Both teratoma testis and small testis occur about three times more frequently on the left side than on the right, and it is suggested that similar etiological factors, which may be associated with gonadal migration, are involved. There seems to be a correlation between the size of a teratoma and the number of tissue types it conta...

This study investigated the probable protective effects of resveratrol (RES), an antioxidant, against methotrexate- (MTX-) induced testis damage. Twenty-four male Sprague Dawley rats were randomly divided into four groups: control, RES, MTX, and MTX + RES groups. Rats were sacrificed at the end of the experiment. Plasma and tissue malondialdehyde (MDA) levels, superoxide dismutase (SOD) and cat...

The present investigation has been performed to obtain a complete distributional map of the oligosaccharidic component of the glycoconjugates in the testis of the human newborn. For this purpose seven eight HRP-conjugated lectins (SBA, DBA, PNA, WGA, OOA, UEAI, LTA and ConA) along with enzymatic treatments, were used. The Sertoli cells were characterized by the same sugar residues detected in t...