Backgroung and Aims: L-Asparaginase II is a cornerstone of treatment protocols for acute lymphoblastic leukemia. Only asparaginase II obtained from E. coli K12 and Erwinia chrysanthemi have been used in human as therapeutic drug. The therapeutic effects of asparaginase II from E. coli K12 and Erwinia chrysanthemi is accompanied by side effects. It is desirable to search for other asparaginase I...

Arctic tundra wetlands may be an important source of dissolved organic carbon (DOC) in rivers and the Ocean under global warming. We investigated stable water isotopes DOC concentration wetlands, tributaries, mainstream at lower reaches Indigirka River northeastern Siberia during summers 2010–2014 to assess complex hydrology role as sources riverine DOC. The had higher values δ 18 O than tribut...

It is known that 19-nor-deoxycorticosterone (19-nor-DOC) is a potent mineralocorticosteroid that is present in urine of rats and humans in a free, i.e., nonconjugated, form. In some forms of hypertension in rats, the levels of free 19-nor-DOC in urine are increased compared with those in urine of normotensive animals. Yet, despite the potential importance of this mineralocorticosteroid in the p...

Abstract Background The meager physicochemical properties like low solubility and dissolution rate of rosuvastatin calcium remain as an obstruction for formulation development. In the present work, we explore evolution cocrystal, which may offer synergetic physico-chemical drug. Cocrystal crafting depends on two possible intermolecular interactions; heteromeric homomeric selection compounds wit...

Activations to pleasant and unpleasant musical stimuli were observed within an extensive neuronal network and different brain structures, as well as in the processing of the syntactic and semantic aspects of the music. Previous studies evidenced a correlation between autonomic activity and emotion evoked by music listening in patients with Disorders of Consciousness (DoC). In this study, we ana...

This review presents an overview of the use of music therapy in neurological early rehabilitation of patients with coma and other disorders of consciousness (DOC) such as unresponsive wakefulness syndrome (UWS) or minimally conscious state (MCS). There is evidence that patients suffering from UWS show emotional processing of auditory information, such as listening to speech. Thus, it seems reas...

The present study was conducted based on the fish species and physicochemical parameters of Eğirdir Lake. Sampling was carried out monthly from January through December 2010 between 9 am and 11 am. The parameters measured were water temperature, depth, secchi disk depth, turbidity, dissolved oxygen, saturation of dissolved oxygen, pH, conductivity, chloride, hardness, calcium, magnesium, bicarb...