OBJECTIVES: In acquired hemophilia (AH), autoantibodies (inhibitors) impede blood coagulation factors leading to severe bleedings. Cornerstones of a successful treatment are the control of bleeding and an eradication of autoantibodies. The present study is an update of our previous documentation of the treatment of high-titer AH patients with severe life-threatening bleeding undergoing the modi...

This article addresses the rebellion of al-Ḥārith b. Surayj, which occurred between 116 and 128 AH (734–46 CE) in Umayyad Khurasan. Combining Bactrian documents, Chinese, Arabic, Persian narratives, numismatic evidence, it highlights local aspect this rebellion. It shows that frontier region Khurasan, Umayyads were only one political group among many other regional powers, all with different pr...

the different constructions of [ah] which is an infinitive are prevalent in the dialect of the historical village of xanik and its neighboring villages. singular second person paradigm in present tense of [ah] infinitive in the dialect is a survivor of sanskrit and old persian languages. some constructions of this infinitive are widely used, because they are attributive verbs meaning is being a...

In this research the relationship between graphitization ability and the carbon equivalent (CE %) of a cast iron have been investigated. The first series of moulds were cast at CE of 3.2% and pouring temperature of 1350°C. The other moulds were cast at different CE% with varying Si content. The graphitization ability( c ) was calculated using the thermodynamics aspects of graphitization and CE%...

Résumé— Une phase primordiale lors de la modélisation d’un système à l’aide d’un perceptron multicouches reste la détermination de la structure du réseau. Dans ce cadre, nous proposons un algorithme d’élagage du réseau basé sur l’utilisation de l’analyse de la variance de la sensibilité de tous les paramètres du réseau. Cet algorithme sera testé sur deux exemples de simulation et ses performanc...

the aim of this study was to evaluate and compare the cytotoxicity induced by two resin-based sealers, 2seal and ah plus, in two osteoblast-like cell lines, mg-63 and saos-2. using sterile discs of both sealers in complete media, 24- and 72-h extracts were prepared. the extracts were exchanged with saos-2 or mg-63 cell culture media at 75% confluence, and after 24 h incubation, cell viability t...

A racemic mixture of R and S enantiomers of praziquantel (PZQ) is currently the treatment of choice for schistosomiasis. Though the S enantiomer and the metabolites are presumed to contribute only a little to the activity of the drug, in-depth side-by-side studies are lacking. The aim of this study was to investigate the in vitro activities of PZQ and its main metabolites, namely, R- and S-cis-...