INTRODUCTION AND AIMS Recent years have witnessed increased attention to how cannabis use impacts the use of other psychoactive substances. The present study examines the use of cannabis as a substitute for alcohol, illicit substances and prescription drugs among 473 adults who use cannabis for therapeutic purposes. DESIGN AND METHODS The Cannabis Access for Medical Purposes Survey is a 414-q...

Complementary medicine methods have a long history, but modern medicine has just recently focused on their possible modes of action. Medicinal leech therapy (MLT) or hirudotherapy, an old technique, has been studied by many researchers for possible effects on various diseases such as inflammatory diseases, osteoarthritis, and after different surgeries. Hirudo medicinalis has widest therapeutic ...

Although nuimerous studies have been reported on the virucidal activity of' various substances used as aerosolic mists or in direct contact with the influenza virus, only two studies have been published describing the action of vapors on viruses, so far as the writers are aware. Remlinger and Bailly (1942) showed that when the viruses of rabies, pseudorabies, or eastern equine encephalomyelitis...

the data of this study was collected from 252 teachers, principals and vice-principals offemales’ high schools in district one through one researcher-administered questionnaire, and was then analyzed. the validity of the questionnaire was approved by seven university professors. cronbach’s alpha was used in order to measure the reliability of the questionnaire. the total calculated alpha was 0....

objective(s) the aim of this study was to investigate the overall effect of cardiac vasoactive factors during coronary occlusion and reperfusion on peripheral vascular tone, using a sequential isolated rabbit heart-ear perfusion model. materials and methods isolated ears were perfused with the effluent of isolated hearts subjected to ischemia (30 min) and reperfusion (180 min, n=6). the compara...

There is strong evidence that the composition of cerebrospinal fluid (CSF) influences brain development, neurogenesis, and behavior. The bidirectional exchange of CSF and interstitial fluid (ISF) across the ependymal and pia-glial membranes is required for these phenomena to occur. Because ISF surrounds the parenchymal compartment, neuroactive substances in the CSF and ISF can influence neurona...

Objective The 1995–2005 balance of EMEA activities in the field of paediatric medicines was evaluated, taking into account the number both of drugs authorised for children and paediatric studies supporting the Marketing Authorisation (MA). Methods Data on drugs authorised by EMEA were extracted from EPARs (European Public Assessment Reports). Active substance, year of approval, anatomical, ther...

A liquid-liquid extraction technique and HPLC-DAD method using a C18 column, 5μm (150x4.6mm i.d.) were developed for toxicological drug screening. home-made “N-acetylparoxetine” is used as internal standard. local UV spectra library of over 130 drugs some their metabolites was created. This covers the main therapeutic classes involved in intoxication cases. The procedure successfully applied to...

The review presents an analysis of publications devoted to the identification biological activity, component composition, pharmacological properties and therapeutic potential various components Curcuma longa plant. This publication was prepared using mostly articles in PubMed, Scopus, Web Science. showed that contains a wide range biologically active substances, including curcuminoids, volatile...

The tested 27 samples of sweet cherry Alexandria variety grown on rootstocks with different growth rates (low-growing, medium and vigorous) had indicators both in marketable conditions the content a complex biologically active substances – sugars, acids, vitamins. According to level accumulation that form nutritional, therapeutic prophylactic properties fruits, variety-rootstock combinations ha...