Recovery of skin function remains a significant clinical challenge for deep burns owing to the severe scar formation and poor appendage regeneration, stem cell therapy has shown great potential injured tissue regeneration. Here, cell-free system burn was explored using mesenchymal paracrine proteins (MSC-PP) polyethylene glycol (PEG) temperature-sensitive hydrogels. A three-dimensional (3D) dyn...

INTRODUCTION Most cases of burns occurring in medical institutions are associated with activities involving heat. It is very difficult to detect these burns. To date, there are few reports on burns occurring in medical institutions. The purpose of this paper was to analyze the etiology of burns occurring in medical institutions and to elucidate the factors affecting burn depth. METHODS We con...

BACKGROUND Burn injuries remain one of the leading causes of injury morbidity and mortality in the World Health Organization's East Mediterranean Region. To provide an overview on the epidemiology of burn injuries in this region, a systematic review was undertaken. METHODS Medline, Embase and CINAHL were searched for publications on burns in this region published between 01/01/1997 and 16/4/2...

Third-degree burn wounds can cause devastating loss of functionality for patients. As such, platform technologies that allow effective wound management are needed. The purpose this study is to describe the use MatriStem™ urinary bladder matrix (UBM)-based products (MicroMatrix® + Cytal®) (MM+C) and a collagen glycosaminoglycan (GAG) product (Integra® Dermal Regeneration Template (DRT)) (DRT) in...

e ach year in the United States, burn injuries result in more than 500,000 hospital emergency department visits and approximately 50,000 acute admissions. Most burn injuries are relatively minor, and patients are discharged following outpatient treatment at the initial medical facility. Of the patients who require hospitalization, about 20,000 are admitted directly or by referral to hospitals w...

Abstract: Burns have a negative effect on quality of life patients and can impair their physiological, psychological, social spiritual well-being. Aim the study: to evaluate self-care education body image among burned patients. Research design: Quasi-experimental design. Setting: The study was conducted in burn department outpatient's clinic, at Assiut Burn Center, city. Sample: Sixty male fema...

Major burn triggers immune dysfunction, which is associated with wound healing complications. Gamma-δ T-cells have been shown to be important in postburn inflammation and wound healing; however, their cytokine phenotype at the burn wound site is unknown. C57BL/6 male mice were subjected to a major burn (25% TBSA, third degree) or sham treatment. At 3 hours, 3 days, and 7 days thereafter, skin s...

BACKGROUND Acute renal failure (ARF) is not a rare occurrence in severe burns and is an important complication leading to an increase in mortality. The severity of the burn is largely determined by the burn size, and severe burns are likely to cause enough loss of extracellular fluid and albumin from plasma volume to produce shock and hypoalbuminemia. HYPOTHESIS We hypothesized that initial s...

Deep wounds, such as third-degree burns, often heal with disfiguring scars that are inelastic and lack sweat glands, oil glands, and hair follicles. Therapies that stimulate the regeneration of blood vessels in the wound could significantly improve the healing process, but remain elusive. Guoming Sun et al. (pp. 20976–20981) assessed whether a biodegradable, dextranbased hydrogel—a 3D network o...