In this study a multicomponent reaction involving carbohydrate derivatives as the main component in order to prepare a new library of polyhydroxy compounds incorporating pyrimidine-fused heterocycles (PFHs) is introduced. A set of polyhydroxy functionalized PFHs were synthesized using multicomponent reactions of sugar (glucose, galactose, arabinose and lactose), barbituric acid and amines. Also...

Recent advances in the study of the p−d radiative and μ−3He weak capture processes are presented and discussed. The three-nucleon bound and scattering states are obtained using the correlated-hyperspherical-harmonics method, with realistic Hamiltonians consisting of the Argonne v14 or Argonne v18 two-nucleon and Tucson-Melbourne or Urbana IX three-nucleon interactions. The electromagnetic and w...

the utilization of hydroxy sodalite (h-sod) as catalyst under solvent-free condition is described for the efficient preparation of tetrahydrobenzo[b]pyrans. these compounds are synthesized by three-component reactions of aldehydes, alkylnitriles and dimedone. h-sod that is the waste-product of zeolite manufacturing process is used as an efficient and a very inexpensive catalyst. furthermore, it...

an efficient synthesis of methyl 2-[2-(alkylimino)-4-oxo-3-phenyl-1,3-thiazolan-5-yliden]acetate derivatives via simple three-component reaction and one-pot reactions between isoquinoline, dimethyl acetylenedicarboxylate and n-phenylthiourea under solvent-free conditions without using any additional catalyst, is described. the mild reaction conditions and good yields and exhibit the synthetic a...

tetra-n-butyl ammonium hydroxide was used as a catalyst for one-pot, three component condensation reactions consisting of aromatic aldehydes, malononitrile and barbituric acid in ethanol:water solvent system at 60oc. current method has major advantages like mild reaction conditions with simple operation, high yields, by using a less toxic and lower costlier catalyst.in conclusion, we have explo...

The stable phosphonate derivatives have easily synthesized by the reactions involving trialkyl(aryl) phosphites and dimethyl acetylenedicarboxylate in the presence of 4-nitrophenol and/or acid chlorides, dialkyl(aryl) phosphites and N-methylimidazole at 70 oC under solventfree conditions.

Economic and environmentally friendly bio-mimetic one-pot three and four-component Knoevenagel-hydrogenation (K-H), five-component Knoevenagel-hydrogenation-alkylation (K-H-A) and six-component Knoevenagel-hydrogenation-alkylation-Huisgen cycloaddition (K-H-A-HC) reactions of aldehydes, CH-acids, o-phenylenediamine, alkyl halides and azides using proline, proline-metal carbonate and proline-met...

Herein we have elucidated unusual and unique nucleophilic conjugate 1,3-addition reactions of surveyed oligoynoates toward phosphines through spectroscopic and single crystal X-ray diffraction analyses of three-component reaction products of oligoynoates, phosphines and aldehydes.