نتایج جستجو برای: throughput nucleotide sequencing

تعداد نتایج: 307622  

Journal: :Cold Spring Harbor Perspectives in Medicine 2018

Journal: :International Journal of Genomics 2017

2017
Ming Li Luyao Gong Dahe Zhao Jian Zhou Hua Xiang

Prokaryotes memorize invader information by incorporating alien DNA as spacers into CRISPR arrays. Although the spacer size has been suggested to be predefined by the architecture of the acquisition complex, there is usually an unexpected heterogeneity. Here, we explored the causes of this heterogeneity in Haloarcula hispanica I-B CRISPR. High-throughput sequencing following adaptation assays d...

Journal: :Plant physiology 2014
Louai Rishmawi Hequan Sun Korbinian Schneeberger Martin Hülskamp Andrea Schrader

In Arabidopsis (Arabidopsis thaliana), branched root hairs are an indicator of defects in root hair tip growth. Among 62 accessions, one accession (Heiligkreuztal2 [HKT2.4]) displayed branched root hairs, suggesting that this accession carries a mutation in a gene of importance for tip growth. We determined 200- to 300-kb mapping intervals using a mapping-by-sequencing approach of F2 pools from...

2013
Delphine Steinbach Michael Alaux Joelle Amselem Nathalie Choisne Sophie Durand Raphaël Flores Aminah-Olivia Keliet Erik Kimmel Nicolas Lapalu Isabelle Luyten Célia Michotey Nacer Mohellibi Cyril Pommier Sébastien Reboux Dorothée Valdenaire Daphné Verdelet Hadi Quesneville

Data integration is a key challenge for modern bioinformatics. It aims to provide biologists with tools to explore relevant data produced by different studies. Large-scale international projects can generate lots of heterogeneous and unrelated data. The challenge is to integrate this information with other publicly available data. Nucleotide sequencing throughput has been improved with new tech...

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