OBJECTIVE Thyroid hemiagenesis is a rare congenital disorder characterized by the absence of a lobe and/or of isthmus. Studies on the association between thyroid hemiagenesis, Graves' disease and differentiated thyroid cancer are rare. CASE PRESENTATION We describe the medical and surgical history of a patient in whom a molecular evaluation was performed. A 36-year-old man presented with symp...

BACKGROUND Thyroid dysfunction is the most common autoimmune endocrine disorder in women of reproductive age, and is associated with menstrual irregularities, anovulation and infertility. Whether it is thyroid function or thyroid autoimmunity that affects functional ovarian reserve (FOR, i.e., the small growing ovarian follicle pool) reflected in anti-Müllerian hormone (AMH) has, however, remai...

INTRODUCTION The link between Hashimoto's thyroiditis and thyroid carcinoma has long been a topic of controversy. OBJECTIVE The aim of our study was to determine the prevalence of thyroid carcinoma and Hashimoto's thyroiditis coexistence in histopathologic material of thyroidectomized patients. METHODS In a retrospective study, the clinicohistopathologic data of 2117 patients (1738 females/...

Graves’ disease is the most common cause of hyperthyroidism in children. It is characterized by suppressed thyroid stimulating hormone and elevated thyroxine levels with varying levels of thyroid stimulating immunoglobulins; and evidence of increased iodine uptake on thyroid scan. It is a multisystem disease with interplay of genetics and environmental factors. Due to the insidious onset of sym...

Laboratory tests are essential for accurate diagnosis and cost-effective management of thyroid disorders. When the clinical suspicion is strong, hormonal levels just confirms the diagnosis. However, in most patients, symptoms are subtle and unspecific, so that only biochemical tests can detect the disorder. The objective of this article is to do a critical analysis of the appropriate use of the...

The association of thyroid disorders and thyroid-related treatments with psychiatric disorders is well known. What is not recognized yet is if antithyroid antibodies may cause psychosis in the absence of encephalopathy and thyroid dysfunction. I report here the cases of 4 patients who developed de-novo psychosis where I found they had high titers of antithyroid antibodies, both antithyroglobuli...

About 30% of children with elevated TSH levels during neonatal screening have a transient form of disorder. On the other hand, it has been reported that subclinical hypothyroidism persists in late childhood in about 30% of children found to be false-positive during neonatal screening. The aim of this study was to determine whether transient thyroid dysfunction and subclinical hypothyroidism det...

Although electroconvulsive therapy (ECT) and lithium are effective treatments for mood disorders, they are both associated with cognitive side-effects that reduce patient compliance and satisfaction. Because both ECT and lithium have significant impact on the hypothalamic-pituitary-thyroid (HPT) axis, at least some of these side-effects may be associated with alterations in HPT activity. There ...

Objective: We made a prospective study evaluating the prevalence of thyroid nodular disease in acromegalic patients. Subjects and methods: Thyroid ultrasound and ultrasound-guided fine needle aspiration biopsy were performed when nodules were detected. Nodules were characterized by cytology and histopathology. Results: We found high prevalence of nodular thyroid disorder, 23/34 (67%) in acromeg...

Antiphospholipid syndrome (APS) is an autoimmune disease that manifests as recurrent venous or arterial thrombosis and/or pregnancy-related complications in the presence of persistent antiphospholipid (aPL) antibodies measured at least 3 months apart. APS occurs either as a primary condition or as a part of an underlying disorder, usually systemic lupus erythematosus (SLE). Otherwise, APS may b...