A 25-year-old woman had total thyroidectomy and iodine-131 ablation therapy for papillary thyroid carcinoma. Whole body imaging on the 7th day of therapeutic activity demonstrated radioiodine uptake in the remnant tissue and intense heterogeneous uptake at the sacral region prominently in the posterior image. Initial interpretation was suspicious for sacral metastasis. Technetium-99m-methylene ...

For many years the recommended therapy for differentiated thyroid carcinoma (DTC), with the exception of unifocal papillary carcinoma <1 cm in diameter, has consisted of (near) total thyroidectomy followed by postoperative radioiodine ablation of thyroid remnant tissue. Even though results from randomized controlled trials are still missing, this combination has proven its worth as a safe and v...

INTRODUCTION Completion thyroidectomy is defined as the surgical removal of the remnant thyroid tissue following procedures of less than total or near-total thyroidectomy. Whether thyroid reoperations are associated with an increased complication risk is controversial. OBJECTIVE A retrospective analysis was done of patients undergoing completion thyroidectomy for cancer of the thyroid who had...

CONTEXT The European Thyroid Association (ETA) has classified posttreatment cervical ultrasound findings in thyroid cancer patients based on their association with disease persistence/recurrence. OBJECTIVE The objective of the study was to assess this classification's ability to predict the growth and persistence of such lesions during active posttreatment surveillance of patients with differ...

Acute hypothyroidism induced by thyroid hormone withdrawal in patients with differentiated thyroid cancer during monitoring for remnant or metastatic disease, seriously affects multiple organs and systems, and especially in severe cases can impair quality of life. Indeed, it may induce untoward cardiovascular effects and can be hazardous in patients with underlying cardiovascular disease, parti...

Differentiated thyroid carcinoma (DTC) of epithelium origin in children and adolescents is an uncommon malignancy with an excellent prognosis. However, pediatric DTC always presents at advanced stages and with higher rates of recurrence. This review aims at the current findings of etiology, diagnosis and therapeutic approach for pediatric DTC. Radiation exposure is the only established risk of ...

In patients with early stage papillary thyroid carcinoma (PTC) who have had a thyroidectomy, the decision must be made to accept or reject radioactive iodine remnant ablation (RRA). Counselling patients about this decision can be challenging, given the medical evidence uncertainties and the complexity of related information. Although physicians are the primary source of medical information for ...

We investigated two structures that are in close association with the pyramidal lobe of thyroid gland. Our investigation was performed using microdissection and histological examination 106 human postmortem specimens. The first structure identified as fibrous band present 28.3% cases. This always associated (which significantly longer thicker when this band) it had a constant hyo-pyramidal exte...

INTRODUCTION We describe here the first reported case of a follicular adenoma arising from a thyroglossal duct remnant within the hyoid bone in Singapore. CLINICAL PICTURE A 32-year-old woman presented with an asymptomatic lump in the anterior midline of her neck of three months' duration. CT scan showed an expansile lesion localised to the medulla of the body of the hyoid. TREATMENT A well...