OBJECTIVE To determine whether estrogen replacement therapy (ERT) adversely affected outcome of breast cancer survivors. METHOD A prospective descriptive study of all breast cancer survivors who requested ERT because of intractable menopausal symptoms. All patients presented voluntarily as gynecological outpatients and were all given oral continuous opposed ERT: 20 premarin and medroxyprogest...

The objective of this study is to explore the effects of acupuncture and auricular acupressure in relieving menopausal hot flashes of bilaterally ovariectomized Chinese women. Between May 2006 and March 2008, 46 bilaterally ovariectomized Chinese women were randomized into an acupuncture and auricular acupressure group (n = 21) and a hormone replacement therapy (HRT) group (Tibolone, n = 25). E...

Endometrial carcinoma is often listed in data sheets as an absolute contraindication to hormone replacement therapy. However, observational studies have not shown an increased rate of recurrence or mortality. Thus, it is often used after stage I or II disease. Alternatives such as progestogens, tibolone, raloxifene, venlafaxine and herbal preparations are examined. The use of progestogens is un...

Reviewmethods MEDLINE, EMBASE/Excerpta Medica, and Cochrane Library (all to Jan 2015) and reference lists were searched for randomized controlled trials (RCTs). 47 RCTs (n = 8326) assessing 16 treatment classes (placebo, sham acupuncture, nonoral estrogen plus progestogen, oral estrogen plus progestogen, conjugated estrogens plus bazedoxifene, tibolone, raloxifene, selective serotonin reuptake ...

Many observational studies and experimental and animal studies have demonstrated that estrogen therapy (ET) or hormone therapy (HT) significantly reduces the risk of coronary heart disease. Nonetheless, recent randomized controlled trials and the Nurses' Health Study in secondary prevention demonstrate trends toward an increased risk of cardiovascular events rather than a reduction of risk from...