Many studies have shown the adverse effects of perfluorinated compounds (PFCs) on living organisms. PFCs include groups of perfluorinated sulfonic acids, perfluorinated carboxylic acids, fluorotelomer alcohols, high-molecular weight fluoropolymers and low-molecular weight perfluoroalkanamides. These compounds are chemically very stable and are highly resistant to biological degradation. Current...

Cinnamon bark is commonly used in traditional Japanese herbal medicines (Kampo medicines). The coumarin contained in cinnamon is known to be hepatotoxic, and a tolerable daily intake (TDI) of 0.1 mg/kg/day, has been quantified and used in Europe to insure safety. Risk assessments for hepatotoxicity by the cinnamon contained in foods have been reported. However, no such assessment of cinnamon ba...

PURPOSE Due to changes in the Dutch fortification policy for vitamin D and the vitamin D supplementation advice for infants (10-μg/d for 0-4 year olds), a partially virtual scenario study was conducted to evaluate the risk of excessive vitamin D intake assigning all infants to a 100 % adherence to the supplementation advice and considering the current fortification practice. METHODS Food cons...

Fumonisins are mycotoxins produced by Fusarium species that commonly live in maize. Whereas fungi damage plants, fumonisins cause disease both to cattle breedings and human beings. Law limits set fumonisins tolerable daily intake with respect to several maize based feed and food. Chemical techniques assure the most reliable and accurate measurements, but they are expensive and time consuming. A...

We investigated presence and levels of DDT in 163 breast milk samples from four South African villages where, in three of them, malaria is controlled with DDT-sprayed indoors. Mean ΣDDT levels in breast milk were 18, 11, and 9.5 mg/kg mf (milk fat) from the three DDT-sprayed villages, respectively, including the highest ΣDDT level ever reported for breast milk from South Africa (140 mg/kg mf). ...

This study was implemented to research the aflatoxin M1 (AFM1) level due economic losses and public health concerns resulting from presence of in food. A total 82 raw cow milk samples were randomly obtained dairy farms Burdur they examined terms AFM1 using Enzyme-Linked Immunosorbent Assay (ELISA) method. It found that between 5.06 50.63 ng kg-1 48 (58.5%) analysed average contamination rate 15...

In France, part of the population is overexposed to cadmium by diet. our work, we first revised tolerable daily intake (TDI) 0.36 ?g Cd.kg bw.d.?1 proposed European Food Safety Authority (EFSA), derived from effects on kidneys and based critical urinary Cd concentration 1.0 Cd.g?1 creatinine for humans. After reviewing epidemiological data toxicity published after 2011, bone were selected as ef...

OBJECTIVES Dietary intake of long-chain (LC) n-3 PUFA in developed countries is low compared with recommendations. Fish is naturally rich in LC n-3 PUFA, but is also a dietary source of heavy metals and organic pollutants. We investigated whether the recommendation for LC n-3 PUFA could be reached through fish consumption, without exceeding the provisional tolerable weekly intake of methylmercu...