BACKGROUND: Parkia speciosa seeds have been reported to an anticancer property due the presence of various antioxidant compounds. Since potential uses P. for tongue cancer has not clearly disclosed, we conducted a study investigate properties seed ethanol extract (PSSEE) as well its effect on cardiac cells.METHODS: Tongue rat model were treated with/without Doxorubicin and concentrations PSSEE....

Zinc (Zn)-deficiency (ZD) is implicated in the pathogenesis of human oral-esophageal cancers. Previously, we showed that in ZD mice genetic deletion of cyclooxygenase-2 (Cox-2) enhances N-nitrosomethylbenzylamine-induced forestomach carcinogenesis. By contrast, Cox-2 deletion offers protection in Zn-sufficient (ZS) mice. We hypothesize that ZD activates pathways insensitive to COX-2 inhibition,...

objectives: geographic tongue or migratory glossitis is an inflammatory disorder with unknown etiology. considering the accompanied burning pain, taste dysfunction, and lack of definite cure, it is important to treat this condition symptomatically. the objective of the current study was to compare the efficacy of a combination of 0.05% retinoic acid and 0.1% triamcinolone acetonide with that of...

PURPOSE Previous studies reported an association between an increased risk of tongue cancer and radiation treatment for nasopharyngeal carcinoma (NPC). This study compared the clinicopathologic characteristics and outcomes of tongue squamous cell carcinoma (TSCC) in patients with and without a history of radiotherapy for NPC. MATERIALS AND METHODS From 1965 to 2009, a total of 73 patients wer...

BACKGROUND Postsurgical oral and oropharyngeal cancer patients may experience pharyngeal clearance problems after completion of postoperative radiotherapy. METHODS Swallowing was examined in six patients using videofluoroscopy for up to 1 year after surgery. Biomechanical analysis was used to mark movement of the tongue base and posterior pharyngeal wall during swallowing. RESULTS The major...

The aim of this study was to evaluate the dosimetric characteristics a semi-customized tongue displacement device ( SC TDD) fabricated using 3D printer for patients receiving unilateral head and neck irradiation with intensity-modulated proton therapy (IMPT) assess its feasibility as beam stopper compared standard mouthpiece S MP). Seven consecutive patients, three tonsil cancer, four oral cavi...

Objectives This pilot study aimed to evaluate the agreement between traditional face-to-face Korean medicine (KM) pattern identification and non-face-to-face KM using data from related questionnaires, tongue image, pulse features in patients with cancer. Methods From January June 2020, 16 participants a cancer diagnosis were recruited at one hospital. Three experienced doctors independently dia...

PURPOSE To understand the role of Bcl-2 overexpression in oral tongue squamous cell carcinoma (OTSCC) patients and investigate the efficacy of targeting Bcl-2 in OTSCC. METHODS The expression level of Bcl-2 on normal tongue cells and OTSCC cells were measured by real-time PCR and western blotting. The functional roles of Bcl-2 were examined by MTS, flow cytometry and xenograft cancer mouse mo...