Background One of the major mediators ischemic neuronal cell death is calcium. It has been found that elevated serum calcium associated with a better prognosis in patients stroke. This study highlights association calcium, albumin-corrected and ionic size acute stroke as well severity outcome terms National Institutes Health Stroke Scale (NIHSS) score Barthel Index. Methods cross-sectional was ...

brain mr images tissue segmentation is one of the most important parts of the clinical diagnostic tools. pixel classification methods have been frequently used in the image segmentation with two supervised and unsupervised approaches up to now. supervised segmentation methods lead to high accuracy but they need a large amount of labeled data, which is hard, expensive and slow to obtain. moreove...

Tissue damage after stroke is partly due to disruption of the blood-brain barrier (BBB). Little is known about the role of calcium in modulating BBB disruption. We investigated the effect of hypoxic and aglycemic stress on BBB function and intracellular calcium levels. Bovine brain microvessel endothelial cells were treated with A-23187 to increase intracellular calcium without hypoxia or treat...

We investigated the effects of intravenous application of nimodipine on the neurophysiologic, biochemical, and morphologic consequences of 15 minutes of global cerebral ischemia in seven rabbits. In vivo dialysis of the hippocampus was used to determine changes in extracellular concentrations of extracellular calcium and amino acids and blood-brain barrier permeability. Ischemia without treatme...

Excepting the observations of Loughridge (1) we have been unable to iind data on the calcium content of striped muscle during parathyroid tetany. He found much less calcium in dog muscle during tetany (two animals) than in the muscles after recovery from tetany through treatment with calcium chloride or parathyroid extract (three animals). Katz (2) found 0.0685 parts of calcium per kilo of norm...

Background and Objective: Dysregulation of long-term expression of non-coding RNAs (lncRNAs) has a potential role in progressive brain disorders such as Alzheimer's disease. This study aimed to analyze the apoptosis and expression of 51A and NAT-Rad18 lncRNAs and their target genes in brain tissue and peripheral blood mononuclear cells (PBMCs) of the rat model of AD, before and after memantine ...

background: diabetes is considered as one of the most common chronic disease. studies show that diabetes decreases the activity of antioxidant enzymes. the purpose of this study was to examine the effect of the alcoholic extract of juglans regia leave on brain antioxidant enzymes in streptozotocin-induced diabetic rats. materials and methods: in this study, adult male wistar rats (n=40, weight ...

In this study, linear alkyl-benzene calcium sulfonate nanoparticles were made using linear alkylbenzene. Calcium sulfonate nanoparticles are widely used as an additive in a variety of engine oils and have cleansing, anti-wear and anti-oxidant properties and anti-corrosion properties. In this method, a sulfonation set up was constructed and sulfonation reaction was carried out both directly and ...