نتایج جستجو برای: total lesion glycolysis

تعداد نتایج: 895324  

2003
SERGIUS MORGULIS

Meyerhof (8) has shown that arsenate stimulates the decomposition of carbohydrate and of hexosephosphate esters by the glycolytic enzyme of muscles. This observation brings muscle glycolysis into close relationship with fermentation of sugar by yeast or yeast products. Harden and Young (6) who discovered the stimulating action of the phosphate ion on the process of alcoholic fermentation were l...

2014
Mervi Sepp Niina Sokolova Svetlana Jugai Merle Mandel Pearu Peterson Marko Vendelin

The effective integrated organization of processes in cardiac cells is achieved, in part, by the functional compartmentation of energy transfer processes. Earlier, using permeabilized cardiomyocytes, we demonstrated the existence of tight coupling between some of cardiomyocyte ATPases and glycolysis in rat. In this work, we studied contribution of two membrane ATPases and whether they are coupl...

Journal: :Blood 1975
G B Segel S A Feig B E Glader A Muller P Dutcher D G Nathan

Three models of disturbed erythrocyte metabolism, triose-depleted normal, phosphoglycerate kinase (PGK)-deficient, and pyruvate kinase (PK)-deficient cells, have been studied to examine further the role of PGK in erythrocyte cation transport. Sodium (Na-+) and potassium (K-+) transport were reduced only in cells fully depleted of triose. In such cells the PGK step presumably was inoperative due...

Journal: :iranian journal of basic medical sciences 0
zhixiong fang department of infectious disease, xiangtan city central hospital, xiangtan, people's republic of china langqiu he department of infectious disease, xiangtan city central hospital, xiangtan, people's republic of china hui jia department of infectious disease, xiangtan city central hospital, xiangtan, people's republic of china qiusheng huang department of infectious disease, xiangtan city central hospital, xiangtan, people's republic of china dan chen edong healthcare city hospital of traditional chinese medicine, inefections disease hospital, huangshi, people's republic of china zhiwei zhang cancer research institute, university of south china, key laboratory of cancer cellular and molecular pathology of hunan provincial university, hengyang, people's republic of china

objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...

2015
Takumi Shiraishi James E. Verdone Jessie Huang Ulf D. Kahlert James R. Hernandez Gonzalo Torga Jelani C. Zarif Tamir Epstein Robert Gatenby Annemarie McCartney Jennifer H. Elisseeff Steven M. Mooney Steven S. An Kenneth J. Pienta

The ability of a cancer cell to detach from the primary tumor and move to distant sites is fundamental to a lethal cancer phenotype. Metabolic transformations are associated with highly motile aggressive cellular phenotypes in tumor progression. Here, we report that cancer cell motility requires increased utilization of the glycolytic pathway. Mesenchymal cancer cells exhibited higher aerobic g...

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