INTRODUCTION Clinical diagnosis of acute appendicitis still remains a problem. Delays in diagnosis of acute appendicitis may cause perforation and septic peritonitis which result in increasing morbidity and mortality. The aim of this study was to determine the sensitivity, specificity and the diagnostic value of total serum bilirubin levels as a predictor of acute appendicitis. METHODS In thi...

BACKGROUND Serum bilirubin has anti-inflammatory, antioxidant and immunological properties. It is considered a protective substance against atherosclerotic and microvascular complications of diabetes mellitus (DM). This study was designed to find the association between total serum bilirubin concentration and diabetic retinopathy (DR). METHODS This case control study was conducted in the Depa...

Accepted guidelines for preoperative endoscopic retrograde cholangiopancreatography (ERCP) in gallstone pancreatitis are lacking. Our previous investigations suggested that serum total bilirubin on hospital Day 2 best predicts persisting common bile duct (CBD) stones. We aim to identify an optimal total bilirubin threshold on hospital Day 2 that would predict persisting CBD stones and guide obt...

BACKGROUND Elevated serum bilirubin has been associated with reduced risk of cardiovascular disease (CVD). However, serum bilirubin is also related with several potential confounders related to CVD, such as obesity. Mendelian randomization has been proposed as a method to address challenges to validity from confounding and reverse causality. It utilizes genotype to estimate causal relationships...

glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most important disease of the hexose monophosphate pathway. deficiency of this enzym can lead to hemolysis of red blood cells. our aim was to study the prevalence of g6pd deficiency in relation to neonatal jaundice. we studied 456 clinically icteric neonates laboratory investigations included determination of direct and indirect serum b...

The relation between age and sex and the concentration of bilirubin in serum was evaluated in 6740 men and 11 215 women, ages 13 to 96 years. Mean serum bilirubin concentrations in the men significantly exceeded values in the women over all age groups examined. Further, mean serum bilirubin concentrations were greatest both in males and females in the 19-24 years age group and then declined to ...

hyperbilirubinemia is a common problem in neonates and causes serious complications. thus, serial measurements of bilirubin should be done. this assessment is done through two methods of laboratory measurement in serum sample and transcutaneous bilirubinometer. this descriptive study compared transcutaneous bilirubin assessment and laboratory serum bilirubin. bilirubin level was assessed among ...

Background: Hyperbilirubinemia is one of the most important complications encountered in neonatal units. It has been proposed that phototherapy yields oxidative stress. Therefore, this study was undertaken to survey the levels of antioxidant and oxidative stress in the serum of neonates before and after phototherapy. Methods: This study was performed on thirty-five healthy, late preterm (>35 w...

We used an enzymatic method for measuring total bilirubin in serum. Results by this method varied linearly with bilirubin concentrations to at least 300 mg/L. The day-to-day precision (CV) of the method ranged from less than 1% to about 11% at bilirubin concentrations of 183 and 12 mg/L, respectively. Commonly used anticoagulants, serum preparation materials, and selected drugs had no effect on...