A number of studies (mainly in vitro and in vivo animal models) have examined the interaction of trace elements with DNA. Normal dietary levels of various trace elements are required to prevent the occurrence of oxidative damage, and deficiency may increase susceptibility. Conversely, overload of some trace elements, including copper and iron, has been demonstrated to result in adverse effects....

Trace element levels are associated with the incidence of osteoporotic fractures, but related mechanisms remain unknown. Trace elements may interfere with growth, development and maintenance of bones. Therefore, we investigated whether plasma trace element levels are associated with bone mineral density in elderly males in Beijing. After epidemiologically investigating 91 elderly males with age...

Hidden Actions of Zinc in Diabetes Several essential and numerous non-essential elements affect the development and progression of diabetes. A case in point with the widest implications is the micronutrient zinc, which in addition to its multiple housekeeping functions in cells is critically involved in the biochemistry of pancreatic islets and insulin-sensitive target cells. Genetic susceptibi...

IN certain experiments on iron metabolism, involving the iron-containing protein of egg-yolk, lecitho-vitellin, we planned to make a large number of iron estimations. To conserve our small supply of protein, the preparation of which had involved considerable time and labour, we desired to cut down the size of the sample analysed to the smallest amount on which an accurate iron determination cou...

Importance of iodine and selenium in thyroid metabolism is well known, but the roles of other essential trace elements including copper, zinc, manganese and iron on thyroid hormone homeostasis remain unclear. The aim of this study was to investigate the status of those trace elements in benign thyroid diseases and evaluate possible links between trace element concentrations and thyroid hormones...

A batch experiment was conducted to examine the effects of six low-molecular-weight organic acids on the mobilization of arsenic and trace metals from a range of contaminated soils. The results showed that the organic acids behaved differently when reacting with soil-borne As and trace metals. Oxalic acid and acetic acid had the strongest and weakest capacity to mobilize the investigated elemen...

Background. Alopecia areata (AA) is an autoimmune condition, in which hair is lost from some areas of the body. Though its etiopathogenesis is not fully understood, there are claims that imbalance of trace elements may trigger the onset of AA, by distorting immune functions. In this study, we tried to investigate the relationship between AA and iron, zinc, and copper levels of serum and hair. M...

Spectral analysis by means of Non-LTE model-atmosphere techniques has arrived at a high level of sophistication: fully line-blanketed model atmospheres which consider opacities of all elements from H to Ni allow the reliable determination of photospheric parameters of hot, compact stars. Such models provide a crucial test of stellar evolutionary theory: recent abundance determinations of trace ...

Introduction: Iron plays an important role in physiological processes as a trace element. Today, iron oxide nanoparticles have attracted extensive attention due to their super paramagnetic properties and a variety of potential applications in many fields. The main objective of this study was to evaluate in vitro and in vivo toxic effects of the iron oxide nanoparticles on L929 cell line, kidney...