Background—Healthy but sedentary aging leads to cardiovascular stiffening, whereas life-long endurance training preserves left ventricular (LV) compliance. However, it is unknown whether exercise training started later in life can reverse the effects of sedentary behavior on the heart. Methods and Results—Twelve sedentary seniors and 12 Masters athletes were thoroughly screened for comorbiditie...

The purpose of this study was to investigate the effects of training on aerobic power and the relationship to excess post exercise oxygen consumption (EPOC) after supramaximal exercise. Ten untrained males participated in a six week training study. The subjects performed pre and post training VO2max tests and anaerobic speed tests (ASTs). EPOC volume and EPOC rate components (1 and 2) as well...

Low-volume 'sprint' interval training (SIT) stimulates rapid improvements in muscle oxidative capacity that are comparable to levels reached following traditional endurance training (ET) but no study has examined metabolic adaptations during exercise after these different training strategies. We hypothesized that SIT and ET would induce similar adaptations in markers of skeletal muscle carbohyd...

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Knowledge of what dose-volume histograms can be expected for a previously unseen patient could increase consistency and quality in radiotherapy treatment planning. We propose a machine learning method that uses previous treatment plans to predict such dose-volume histograms. The key to the approach is the framing of dose-volume histograms in a probabilistic setting.The training consists of esti...

tumor cells are dependent on angiogenesis to obtain oxygen and nutrients and also development of their new vascular network. vegf as an important stimulator of angiogenesis and endostatin as an inhibitor play a fundamental role in this process. this study was designed to investigate the effect of six weeks of resistance training on tumor tissue vegf andendostatin in mice with breast cancer. for...